CONST OF ADDICTION RES CTR: SCHIZOPHRENIA, BIPOLAR DISORDER

成瘾缓解措施的持续时间：精神分裂症、双相情感障碍

• 批准号: 6794335
• 负责人: ANTHONY J INFANTE
• 金额: $ 99.87万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794335
• 关键词: bioimaging /biomedical imaging; biomedical facility; bipolar depression; building /facility design /renovation; clinical research; molecular genetics; neuroimaging; neuropsychology; schizophrenia; training; university

DESCRIPTION (provided by applicant): The applicant requests $2,996,175 to build a dedicated two-floor research facility entitled "START Center" (17,225 sq. ft.) at the UTHSCSA. The START Center's mission is to provide an outstanding addiction and health disparities research and research training environment; in partnership with the Hispanic Center of Excellence; fusing collaborative neuroscience, behavioral, and community-based research into the underpinnings of addictive disorders; medication development to treat these disorders; and addressing minority health disparities in these disorders. Specifically, plans are to: 1) develop a centralized state-of-the-art research facility thereby forging increased interaction between scientists and increasing their productivity and efficiency; 2) provide contiguous animal and human laboratories for programmatic medications development, and increased understanding of mechanistic processes associated with both the disease states and the therapeutic medications; 3) provide biochemical and molecular genetics laboratories to support the pre-clinical and clinical neurobehavioral research, thereby inter-weaving research knowledge in these areas; 4) provide a state-of-the-art clinical research center for conducting large National Institutes of Health (NIH)-sponsored studies with centralized core statistical, administrative, and research support; 5) expand the research training program of the Hispanic Center of Excellence at UTHSCSA through direct collaboration with START Center investigators; 6) expand community-based minority health and health disparities research pertaining to addictive disorders in partnership with the Hispanic Center of Excellence; and 7) enhance collaborative preclinical and clinical neuroimaging studies in the Research Imaging Center at UTHSCSA. The START Center's research addresses national needs in the areas of addiction and mental health. The START Center will greatly benefit the research goals of sixteen funded researchers at UTHSCSA with inadequate space who are currently housed at separate sites on campus. The START Center will enable recruitment of three new faculty critical to the development of the program. Consolidation of START Center investigators within this facility will benefit students, fellows, physicians, and other health workers including those affiliated with the Hispanic Center of Excellence. The Principal Investigator (PI) will be the Associate Dean for Research of the Medical School, Anthony J. Infante, M.D. The Project Coordinator will be Bankole A. Johnson, M.D., Ph.D. The University will contribute 50 percent of the projected costs.

描述（由申请人提供）：申请人要求在UTHSCSA上建立一个专门的两层研究设施，旨在建造一个专用的两层研究设施（17,225平方英尺）。起步中心的任务是提供出色的成瘾和健康差异研究和研究培训环境；与西班牙裔卓越中心合作；融合对成瘾性疾病基础的基础神经科学，行为和基于社区的研究；治疗这些疾病的药物开发；并解决这些疾病中的少数族裔健康差异。具体而言，计划是：1）开发一个集中的最先进的研究机构，从而锻造科学家之间的相互作用增加，并提高其生产率和效率； 2）提供连续的动物和人类实验室来进行程序化药物的开发，并增加对与疾病状态和治疗药物相关的机械过程的理解； 3）提供生化和分子遗传学实验室，以支持临床前和临床神经行为研究，从而在这些领域中交往研究知识； 4）提供了一个最先进的临床研究中心，用于开展大型国立卫生研究院（NIH）赞助的研究，并提供集中的核心统计，行政和研究支持； 5）通过与Start Center调查人员直接合作，扩大了UTHSCSA西班牙裔卓越中心的研究培训计划； 6）与西班牙裔卓越中心合作，扩大与成瘾性疾病有关的基于社区的少数民族健康和健康差异研究； 7）在UTHSCSA的研究成像中心增强了临床前和临床神经影像学研究。起始中心的研究解决了成瘾和心理健康领域的国家需求。起步中心将极大地使UTHSCSA的16名资助研究人员的研究目标受益，而空间不足，这些空间目前位于校园的单独地点。起步中心将使三个对计划开发至关重要的新教师招募。该设施内的起始中心调查人员的合并将使学生，研究员，医生和其他卫生工作者受益，包括与西班牙裔卓越中心相关的人。首席研究员（PI）将成为医学院研究的副院长，Anthony J. Infante，M.D。项目协调员将是Bankole A. Johnson，M.D。，博士学位。该大学将贡献预计成本的50％。