CONST OF ADDICTION RES CTR: SCHIZOPHRENIA, BIPOLAR DISORDER

成瘾缓解措施的持续时间：精神分裂症、双相情感障碍

• 批准号: 6794335
• 负责人: ANTHONY J INFANTE
• 金额: $ 99.87万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794335
• 关键词: bioimaging /biomedical imaging; biomedical facility; bipolar depression; building /facility design /renovation; clinical research; molecular genetics; neuroimaging; neuropsychology; schizophrenia; training; university

DESCRIPTION (provided by applicant): The applicant requests $2,996,175 to build a dedicated two-floor research facility entitled "START Center" (17,225 sq. ft.) at the UTHSCSA. The START Center's mission is to provide an outstanding addiction and health disparities research and research training environment; in partnership with the Hispanic Center of Excellence; fusing collaborative neuroscience, behavioral, and community-based research into the underpinnings of addictive disorders; medication development to treat these disorders; and addressing minority health disparities in these disorders. Specifically, plans are to: 1) develop a centralized state-of-the-art research facility thereby forging increased interaction between scientists and increasing their productivity and efficiency; 2) provide contiguous animal and human laboratories for programmatic medications development, and increased understanding of mechanistic processes associated with both the disease states and the therapeutic medications; 3) provide biochemical and molecular genetics laboratories to support the pre-clinical and clinical neurobehavioral research, thereby inter-weaving research knowledge in these areas; 4) provide a state-of-the-art clinical research center for conducting large National Institutes of Health (NIH)-sponsored studies with centralized core statistical, administrative, and research support; 5) expand the research training program of the Hispanic Center of Excellence at UTHSCSA through direct collaboration with START Center investigators; 6) expand community-based minority health and health disparities research pertaining to addictive disorders in partnership with the Hispanic Center of Excellence; and 7) enhance collaborative preclinical and clinical neuroimaging studies in the Research Imaging Center at UTHSCSA. The START Center's research addresses national needs in the areas of addiction and mental health. The START Center will greatly benefit the research goals of sixteen funded researchers at UTHSCSA with inadequate space who are currently housed at separate sites on campus. The START Center will enable recruitment of three new faculty critical to the development of the program. Consolidation of START Center investigators within this facility will benefit students, fellows, physicians, and other health workers including those affiliated with the Hispanic Center of Excellence. The Principal Investigator (PI) will be the Associate Dean for Research of the Medical School, Anthony J. Infante, M.D. The Project Coordinator will be Bankole A. Johnson, M.D., Ph.D. The University will contribute 50 percent of the projected costs.

描述（由申请人提供）：申请人请求 2,996,175 美元在 UTHSCSA 建造一个名为“START 中心”（17,225 平方英尺）的专用两层研究设施。 START 中心的使命是提供出色的成瘾和健康差异研究和研究培训环境；与西班牙裔卓越中心合作；将协作神经科学、行为和基于社区的研究融合到成瘾性疾病的基础上；治疗这些疾病的药物开发；并解决这些疾病中少数群体的健康差异。具体来说，计划是：1）开发一个集中的、最先进的研究设施，从而加强科学家之间的互动，提高他们的生产力和效率； 2）提供连续的动物和人类实验室用于程序性药物开发，并增加对与疾病状态和治疗药物相关的机械过程的理解； 3）提供生化和分子遗传学实验室来支持临床前和临床神经行为研究，从而交织这些领域的研究知识； 4) 提供最先进的临床研究中心，用于开展美国国立卫生研究院 (NIH) 资助的大型研究，并提供集中的核心统计、管理和研究支持； 5) 通过与 START 中心研究人员的直接合作，扩大 UTHSCSA 西班牙裔卓越中心的研究培训计划； 6) 与西班牙裔卓越中心合作，扩大基于社区的少数族裔健康和与成瘾性疾病有关的健康差异研究； 7) 加强 UTHSCSA 影像研究中心的临床前和临床神经影像协作研究。 START 中心的研究满足了国家在成瘾和心理健康领域的需求。 START 中心将极大地有利于 UTHSCSA 的 16 名受资助研究人员的研究目标，这些研究人员目前居住在校园的不同地点，但空间不足。 START 中心将招募三名对于该项目的发展至关重要的新教师。 START 中心研究人员在该设施内的整合将使学生、研究员、医生和其他卫生工作者（包括隶属于西班牙裔卓越中心的人员）受益。首席研究员 (PI) 为医学院研究副院长 Anthony J. Infante, M.D.。项目协调员为 Bankole A. Johnson, M.D., Ph.D.。大学将承担预计费用的 50%。