CONST OF ADDICTION RES CTR: OPIOID

成瘾持续缓解措施：阿片类药物

• 批准号: 6794336
• 负责人: ANTHONY J INFANTE
• 金额: $ 99.87万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794336
• 关键词: bioimaging /biomedical imaging; biomedical facility; clinical research; community; drug abuse therapy; health disparity; mental health; molecular genetics; neuroimaging; neuropsychology; training; university

DESCRIPTION (provided by applicant): The applicant requests $2,996,175 to build a dedicated two-floor research facility entitled "START Center" (17,225 sq. ft.) at the UTHSCSA. The START Center's mission is to provide an outstanding addiction and health disparities research and research training environment; in partnership with the Hispanic Center of Excellence; fusing collaborative neuroscience, behavioral, and community-based research into the underpinnings of addictive disorders; medication development to treat these disorders; and addressing minority health disparities in these disorders. Specifically, plans are to: 1) develop a centralized state-of-the-art research facility thereby forging increased interaction between scientists and increasing their productivity and efficiency; 2) provide contiguous animal and human laboratories for programmatic medications development, and increased understanding of mechanistic processes associated with both the disease states and the therapeutic medications; 3) provide biochemical and molecular genetics laboratories to support the pre-clinical and clinical neurobehavioral research, thereby inter-weaving research knowledge in these areas; 4) provide a state-of-the-art clinical research center for conducting large National Institutes of Health (NIH)-sponsored studies with centralized core statistical, administrative, and research support; 5) expand the research training program of the Hispanic Center of Excellence at UTHSCSA through direct collaboration with START Center investigators; 6) expand community-based minority health and health disparities research pertaining to addictive disorders in partnership with the Hispanic Center of Excellence; and 7) enhance collaborative preclinical and clinical neuroimaging studies in the Research Imaging Center at UTHSCSA. The START Center's research addresses national needs in the areas of addiction and mental health. The START Center will greatly benefit the research goals of sixteen funded researchers at UTHSCSA with inadequate space who are currently housed at separate sites on campus. The START Center will enable recruitment of three new faculty critical to the development of the program. Consolidation of START Center investigators within this facility will benefit students, fellows, physicians, and other health workers including those affiliated with the Hispanic Center of Excellence. The Principal Investigator (PI) will be the Associate Dean for Research of the Medical School, Anthony J. Infante, M.D. The Project Coordinator will be Bankole A. Johnson, M.D., Ph.D. The University will contribute 50 percent of the projected costs.

描述（由申请人提供）：申请人要求2,996,175美元用于建造一个名为“START中心”的专用两层研究设施（17,225平方米）。)。START中心的使命是提供一个出色的成瘾和健康差异研究和研究培训环境；与西班牙裔卓越中心合作；将协作神经科学、行为和基于社区的研究融入成瘾性疾病的基础；治疗这些疾病的药物开发；解决这些疾病中少数群体的健康差异。具体来说，计划是：1)发展一个集中的最先进的研究设施，从而加强科学家之间的互动，提高他们的生产力和效率；2)为程序化药物开发提供连续的动物和人类实验室，并增加对与疾病状态和治疗药物相关的机制过程的理解；3)提供生化和分子遗传学实验室，支持临床前和临床神经行为研究，从而将这些领域的研究知识相互交织；4)提供最先进的临床研究中心，以开展由美国国立卫生研究院（NIH）资助的大型研究，并提供集中的核心统计、行政和研究支持；5)通过与START中心研究人员的直接合作，扩大UTHSCSA西班牙裔卓越中心的研究培训计划；6)与西班牙裔卓越中心合作，扩大与成瘾性疾病有关的社区少数民族健康和健康差异研究；7)加强UTHSCSA研究成像中心的临床前和临床神经影像学合作研究。START中心的研究解决了成瘾和心理健康领域的国家需求。START中心将极大地有利于UTHSCSA的16名受资助的研究人员的研究目标，这些研究人员目前住在校园的不同地点。START中心将招募三名对项目发展至关重要的新教员。在该设施内整合START中心调查员将有利于学生，研究员，医生和其他卫生工作者，包括西班牙裔卓越中心的附属人员。首席研究员（PI）将是医学院负责研究的副院长Anthony J. Infante，医学博士。项目协调员将是Bankole A. Johnson，医学博士。大学将承担50%的预计费用。