RES BLDG RENOVATION: AGING

RES 大楼改造：老化

• 批准号: 6794346
• 负责人: J WAYNE STREILEIN
• 金额: $ 35.54万
• 依托单位: SCHEPENS EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794346
• 关键词: aging; biomedical facility; building /facility design /renovation; immunity; inflammation; molecular biology; retina; transplantation

DESCRIPTION (Provided by applicant): The Schepens Eye Research Institute intends to renovate its 64,000 sq. ft. laboratory building built approximately 40 years ago. The goal of this program is to provide modern laboratories and support facilities to enable individual scientists, alone and in collaborations, to attack with powerful modern scientific disciplines the problems of disease pathology for which no prevention or cure now exists. The renovation program consists of two phases; the first of which is underway and is designed to reconstruct the building's infrastructure heating, ventilation, and air-conditioning (HVAC); plumbing; and electricity systems; etc. The second phase is designed to renovate the three laboratory floors (16,000 sq. ft. each) in three sequential segments. Segments one and two, which were the subject of the previous application that was funded in 2000, had the goal of renovating laboratories on three separate floors for 14 Principal Investigators (PIs) with research activities in ocular immunity, inflammation and transplantation (Second Floor North), ocular surface diseases (Third Floor), and biology of the retina (First Floor North). Segment 3a, which is the subject of the current application, has the goal of renovating approximately 10,000 sq. ft. of space on the second floor South of laboratory building in order to provide high quality laboratories for four PIs whose research focus is ocular immunity, inflammation and transplantation. Upon completion, all investigators at the Institute working in immunity, inflammation and transplantation will be located on the second floor. In addition, the renovated area will include: 1) a new molecular biology core facility; 2) a glassware washing facility; and 3) a conference room and communication center. Approximately $1.8 million toward a total cost of $3.9 million for Segment 3a is requested. Once Segment 3a is accomplished, space will be available to carry out Segment 3b. At the completion of the renovation program, the Institute will have a physical facility sufficient to meet present research needs.

描述（由申请人提供）：Schepens眼科研究所打算对其64,000平方英尺的建筑进行翻新。大约40年前建造的实验室大楼。该计划的目标是提供现代化实验室和辅助设施，使科学家个人能够单独或合作，利用强大的现代科学学科来解决目前无法预防或治愈的疾病病理学问题。改造方案包括两个阶段；第一个项目正在进行中，旨在重建建筑的基础设施供暖、通风和空调（HVAC）；管道;电力系统；等。第二阶段的设计是翻新三个实验室楼层（16,000平方英尺）。（每个）分成三个连续的部分。第一部分和第二部分是2000年资助的前一个申请的主题，其目标是在三个独立的楼层为14名主要研究人员（pi）翻新实验室，进行眼部免疫、炎症和移植（二楼北）、眼表疾病（三楼）和视网膜生物学（一楼北）的研究活动。3a部分是当前申请的主题，其目标是改造约10,000平方英尺。在实验楼南楼二楼，为四个研究重点是眼免疫、炎症和移植的pi提供高质量的实验室。建成后，研究所从事免疫、炎症和移植研究的所有研究人员都将在二楼工作。此外，改造后的区域将包括：1)一个新的分子生物学核心设施；2)玻璃器皿清洗设施；3)会议室和通讯中心。3a段的总费用为390万美元，其中约180万美元被要求提供。一旦3a段完成，空间将可用来执行3b段。在整修方案完成后，研究所将拥有一个足以满足目前研究需要的物理设施。