CONTINUED RENOVATION OF RESEARCH BLDG

描述(申请人提供)：谢彭斯眼科研究所 打算翻新其6.4万平方米。英国《金融时报》实验室大楼大约建于 40年前。该计划的目标是提供现代化的实验室和 支持设施，使个别科学家能够单独和在 合作，用强大的现代科学学科攻击 目前尚无预防或治愈方法的疾病病理学问题。这个 翻新计划由两个阶段组成；第一阶段正在进行中， 旨在重建大楼的基础设施供暖、通风、 和空调(暖通空调)；管道；电力系统；等等 二期工程旨在翻新三个实验室楼层(16,000平方米。 英国《金融时报》每个)在三个连续的段中。第一段和第二段，这是 上一项申请是在2000年资助的，其目标是 为14名校长改造三个独立楼层的实验室 研究人员(PI)，从事眼睛免疫、炎症方面的研究活动 和移植(二楼北)，眼表疾病(第三 一楼)和视网膜生物学(一楼北)。数据段3a，即 目前申请的主题，目标是翻新 大约10,000平方米英国《金融时报》实验室南面二楼的空间 为四个私人投资机构提供高质量的实验室 研究重点是眼免疫、炎症和移植。vt.在.的基础上 完成，研究所的所有调查人员都在豁免权工作， 炎症和移植将位于二楼。在……里面 此外，翻新后的区域将包括：1)新的分子生物学核心 设施；2)玻璃器皿清洗设施；3)会议室和 通讯中心。大约180万美元，总成本为390万美元 为段3a请求100,000。一旦段3a完成，空间 将可用于执行3b段。在完成 翻新计划，研究所将拥有足够的有形设施 满足当前的研究需求。

DESCRIPTION (Provided by applicant): The Schepens Eye Research Institute intends to renovate its 64,000 sq. ft. laboratory building built approximately 40 years ago. The goal of this program is to provide modern laboratories and support facilities to enable individual scientists, alone and in collaborations, to attack with powerful modern scientific disciplines the problems of disease pathology for which no prevention or cure now exists. The renovation program consists of two phases; the first of which is underway and is designed to reconstruct the building's infrastructure heating, ventilation, and air-conditioning (HVAC); plumbing; and electricity systems; etc. The second phase is designed to renovate the three laboratory floors (16,000 sq. ft. each) in three sequential segments. Segments one and two, which were the subject of the previous application that was funded in 2000, had the goal of renovating laboratories on three separate floors for 14 Principal Investigators (PIs) with research activities in ocular immunity, inflammation and transplantation (Second Floor North), ocular surface diseases (Third Floor), and biology of the retina (First Floor North). Segment 3a, which is the subject of the current application, has the goal of renovating approximately 10,000 sq. ft. of space on the second floor South of laboratory building in order to provide high quality laboratories for four PIs whose research focus is ocular immunity, inflammation and transplantation. Upon completion, all investigators at the Institute working in immunity, inflammation and transplantation will be located on the second floor. In addition, the renovated area will include: 1) a new molecular biology core facility; 2) a glassware washing facility; and 3) a conference room and communication center. Approximately $1.8 million toward a total cost of $3.9 million for Segment 3a is requested. Once Segment 3a is accomplished, space will be available to carry out Segment 3b. At the completion of the renovation program, the Institute will have a physical facility sufficient to meet present research needs.