RES BLDG RENOVATION: CANCER

RES 大楼改造：癌症

• 批准号: 6794347
• 负责人: J WAYNE STREILEIN
• 金额: $ 35.54万
• 依托单位: SCHEPENS EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794347
• 关键词: biomedical facility; building /facility design /renovation; immunity; inflammation; molecular biology; neoplasm /cancer transplantation; retina

DESCRIPTION (Provided by applicant): The Schepens Eye Research Institute intends to renovate its 64,000 sq. ft. laboratory building built approximately 40 years ago. The goal of this program is to provide modern laboratories and support facilities to enable individual scientists, alone and in collaborations, to attack with powerful modern scientific disciplines the problems of disease pathology for which no prevention or cure now exists. The renovation program consists of two phases; the first of which is underway and is designed to reconstruct the building's infrastructure heating, ventilation, and air-conditioning (HVAC); plumbing; and electricity systems; etc. The second phase is designed to renovate the three laboratory floors (16,000 sq. ft. each) in three sequential segments. Segments one and two, which were the subject of the previous application that was funded in 2000, had the goal of renovating laboratories on three separate floors for 14 Principal Investigators (PIs) with research activities in ocular immunity, inflammation and transplantation (Second Floor North), ocular surface diseases (Third Floor), and biology of the retina (First Floor North). Segment 3a, which is the subject of the current application, has the goal of renovating approximately 10,000 sq. ft. of space on the second floor South of laboratory building in order to provide high quality laboratories for four PIs whose research focus is ocular immunity, inflammation and transplantation. Upon completion, all investigators at the Institute working in immunity, inflammation and transplantation will be located on the second floor. In addition, the renovated area will include: 1) a new molecular biology core facility; 2) a glassware washing facility; and 3) a conference room and communication center. Approximately $1.8 million toward a total cost of $3.9 million for Segment 3a is requested. Once Segment 3a is accomplished, space will be available to carry out Segment 3b. At the completion of the renovation program, the Institute will have a physical facility sufficient to meet present research needs.

描述（由申请人提供）：Schepens 眼科研究所打算翻新其大约 40 年前建造的 64,000 平方英尺的实验室大楼。该计划的目标是提供现代化的实验室和支持设施，使科学家能够单独或合作地利用强大的现代科学学科来解决目前尚无预防或治愈方法的疾病病理学问题。改造计划分为两个阶段；第一个项目正在进行中，旨在重建建筑物的供暖、通风和空调 (HVAC) 基础设施；管道；和电力系统；第二阶段旨在分三个连续部分翻新三个实验室楼层（每层 16,000 平方英尺）。第一和第二部分是 2000 年资助的先前申请的主题，其目标是为 14 名首席研究员 (PI) 翻新位于三个不同楼层的实验室，从事眼部免疫、炎症和移植（二楼北）、眼表疾病（三楼）和视网膜生物学（一楼北）方面的研究活动。 3a部分是本次申请的主体，目标是改造实验室大楼南二楼约10,000平方英尺的空间，为四名研究重点为眼部免疫、炎症和移植的PI提供高质量的实验室。建成后，研究所所有从事免疫、炎症和移植研究的研究人员将集中在二楼。此外，改造后的区域将包括：1）新的分子生物学核心设施； 2）玻璃器皿清洗设施； 3) 会议室和通讯中心。 3a 部分的总成本为 390 万美元，需要约 180 万美元。一旦完成第 3a 部分，将有空间可用于执行第 3b 部分。改造工程完成后，研究所将拥有足以满足当前研究需求的物理设施。