EXERCISE AND CALCIUM EFFECT ON THE GROWING BONE

描述(改编自申请人的描述)：预防 骨质疏松症依赖于最大骨量和最小骨量 随之而来的骨质流失。在儿童和青春期，目标是 增加峰值骨量。这项研究的目的是调查 乳制品对骨骼负荷和补钙的影响 产品对青春期前骨骼中的骨矿物质有促进作用。第四 年级的女孩和男孩将从两所小学中选出。每个人 学校每个年级有4-5个班级，每个年级有80-125名儿童。这个 干预措施将在20个月内跨越两个8个月的区块，并将 分两个阶段进行。第一阶段将是骨骼负荷和控制 组。第二阶段将是骨骼负荷加钙干预和 单纯钙干预组。骨骼负荷干预计划 将包括各种跳跃和跳框活动，旨在 刺激骨形成。累进计划，最多15人 分钟，跳跃活动将被纳入身体 每周开两次课的教育课。饮食小组将是 他们被指示每天在饮食中添加1,200毫克的乳制品。 研究对象的纳入标准为：青春期前、非吸烟者、 没有骨科问题，也没有代谢史 可能影响骨骼新陈代谢的疾病或疗法。以下是数据 将在0、8和20个月时收集：饮食记录、钙和 体力活动史、骨骼扫描、身体成分和皮肤晒黑阶段。 其主要目标是调查初级阶段的 学校跳绳加钙干预项目对老年人骨量的影响 腰椎、股骨近端和整个身体 青春期前的男孩和女孩。第二个目标是比较骨骼 美国儿童对加拿大儿童的矿物质积累经历了类似的 骨骼加载方案。

DESCRIPTION (Adapted from applicant's description): The prevention of osteoporosis is dependent upon maximizing peak bone mass and minimizing subsequent bone loss. During childhood and adolescence, the goal is to increase peak bone mass. The purpose of the study is to investigate the influence of skeletal loading and calcium supplementation with dairy products on bone mineral accretion in the prepubescent skeleton. Fourth grade girls and boys will be selected from two elementary schools. Each school has 4-5 classes per grade with 80-125 children per grade level. The interventions will span two 8-month blocks in a 20-month period and will be conducted in two phases. Phase 1 will be skeletal loading and control groups. Phase 2 will be skeletal loading plus calcium intervention and calcium intervention only groups. The skeletal loading intervention program will include a variety of skipping and box jumping activities designed to stimulate bone formation. A progressive program, to a maximum of fifteen minutes, of jumping activities will be incorporated into the physical education classes that meet twice a week. The dietary groups will be instructed to supplement their diets with dairy products to 1,200 mg/day. The inclusion criteria for the subjects will be: prepubescent, non-smokers, no orthopedic problems, and absence of previous history of metabolic diseases or therapies that may affect bone metabolism. The following data will be gathered at 0, 8, and 20 months: dietary records, calcium & physical activity histories, bone scans, body composition, and Tanner stage. The primary objective is to investigate the effect of an elementary school-based jump rope and calcium intervention program on bone accrual at the lumbar spine, the proximal femur and for the total body in a group of prepubertal boys and girls. A secondary objective is to compare the bone mineral accretion of U.S. children to Canadian children undergoing a similar skeletal loading protocol.