Development and Neural Bases of Sequence Learning

描述(申请者提供)：本次修订的研究生涯奖 申请将为申请人提供额外的培训和 使用Function进行独立职业生涯所需的指导 用于检查发展认知问题的神经成像技术 神经科学。申请人是一名精神病学心理学讲师， 儿童心理学博士培训和解剖学博士后培训 以及儿童功能磁共振成像(MRI)技术。她 研究重点是儿童时期学习和记忆技能的大脑基础， 尤其是内隐序列学习的发展。海流 提案寻求建立在这种发展专门知识的基础上，并进一步 考生在认知科学和高级技术方面的理论思考 在功能磁共振领域的技能，以及整合行为， 电生理和功能磁共振成像技术检测脑神经基础的研究 儿童的顺序学习。她将在设计、指挥和培训方面接受指导 行为和神经成像研究的分析，试图解决 文献综述了内隐学习的发展和神经基础 跨越童年。研究将涉及规范性发展，并将包括 1)开发基于眼动的序列学习任务 适合所有年龄段的人；2)探索 通过操纵儿童学习系统的特征来限制儿童学习系统 要学习的信息，以及3)并行电生理和 神经成像研究以评估神经的时间和空间动力学 系统从属于跨开发的顺序学习。的总体目的 建议的研究是为了加深我们对神经系统的了解。 潜藏着各种形式的学习和记忆的发展。最终， 这项工作的长期目标是为 了解这些神经系统发育过程中的干扰 会导致发育障碍。

DESCRIPTION (provided by applicant): This revised Research Career Award application will provide the applicant with the additional training and mentoring necessary to pursue an independent career using functional neuroimaging techniques to examine issues in developmental cognitive neuroscience. The applicant is an Instructor of Psychology in Psychiatry with doctoral training in child psychology and postdoctoral training in anatomical and functional magnetic resonance imaging (MRI) techniques with children. Her work focuses on the brain bases of learning and memory skills across childhood, in particular, the development of implicit sequence learning. The current proposal seeks to build on this developmental expertise and to further the candidate's theoretical thinking in cognitive science and advanced technical skills in the area of functional MRI, and the integration of behavioral, electrophysiological and fMRI approaches to examining the neural bases of sequence learning in children. She will be mentored in the design, conduct, and analysis of behavioral and neuroimaging studies that attempt to address gaps in the literature examining the development and neural bases of implicit learning across childhood. Studies will address normative development and will include 1) development of an eye movement based sequence learning task that is appropriate for all age ranges; 2) behavioral experiments that probe the constraints of child learning systems by manipulating characteristics of the information to be learned, and 3) parallel electrophysiological and neuroimaging studies to assess the temporal and spatial dynamics of the neural systems subserving sequence learning across development. The overall purpose of the proposedstudies is to further our understanding of the neural systems underlying the development of various forms of learning and memory. Ultimately, the long-term goal of this work is to lay the critical foundation for understanding how disruptions in the development of these neural systems may give rise to developmental disorders.