Development and Neural Bases of Sequence Learning

描述（由申请人提供）：此修订的研究职业奖 申请将为申请人提供额外的培训， 必要的指导，以追求独立的职业生涯使用功能 神经成像技术来检查发展认知问题 神经科学申请人是精神病学心理学讲师， 儿童心理学博士培训和解剖学博士后培训 和功能性磁共振成像（MRI）技术。她 工作重点是儿童时期学习和记忆技能的大脑基础， 尤其是内隐序列学习的发展。当前 该提案寻求在这一发展专门知识的基础上， 候选人在认知科学和先进技术方面的理论思维 功能性磁共振成像领域的技能，以及行为， 电生理学和功能磁共振成像方法来检查的神经基础， 儿童的顺序学习她将在设计，行为， 分析行为和神经影像学研究，试图解决差距， 研究内隐学习的发展和神经基础的文献 穿越童年研究将涉及规范发展，并将包括 1)开发基于眼动的序列学习任务， 适合所有年龄段; 2）行为实验，探索 儿童学习系统的限制，通过操纵的特点， 要学习的信息，以及3）并行的电生理学和 神经影像学研究，以评估神经的时间和空间动态 系统在整个发展过程中促进序列学习。的总体目的 这项研究的目的是为了进一步了解神经系统 是各种学习和记忆发展的基础。最后， 这项工作的长期目标是为以下方面奠定关键基础： 了解这些神经系统发育中的干扰如何 会导致发育障碍

DESCRIPTION (provided by applicant): This revised Research Career Award application will provide the applicant with the additional training and mentoring necessary to pursue an independent career using functional neuroimaging techniques to examine issues in developmental cognitive neuroscience. The applicant is an Instructor of Psychology in Psychiatry with doctoral training in child psychology and postdoctoral training in anatomical and functional magnetic resonance imaging (MRI) techniques with children. Her work focuses on the brain bases of learning and memory skills across childhood, in particular, the development of implicit sequence learning. The current proposal seeks to build on this developmental expertise and to further the candidate's theoretical thinking in cognitive science and advanced technical skills in the area of functional MRI, and the integration of behavioral, electrophysiological and fMRI approaches to examining the neural bases of sequence learning in children. She will be mentored in the design, conduct, and analysis of behavioral and neuroimaging studies that attempt to address gaps in the literature examining the development and neural bases of implicit learning across childhood. Studies will address normative development and will include 1) development of an eye movement based sequence learning task that is appropriate for all age ranges; 2) behavioral experiments that probe the constraints of child learning systems by manipulating characteristics of the information to be learned, and 3) parallel electrophysiological and neuroimaging studies to assess the temporal and spatial dynamics of the neural systems subserving sequence learning across development. The overall purpose of the proposedstudies is to further our understanding of the neural systems underlying the development of various forms of learning and memory. Ultimately, the long-term goal of this work is to lay the critical foundation for understanding how disruptions in the development of these neural systems may give rise to developmental disorders.