African-American Women's Response to Physical Activity

描述：(申请人提供)这份为期3年的建议书的近期目标 是加强应聘者的研究知识和技能，并提供 在体力活动的研究中综合这些因素的机会 与心血管疾病控制和预防有关的其他结果 妇女，特别是少数民族妇女。总体目标是生产 一名独立调查员，其职业生涯致力于制作和 将对少数群体的健康产生影响的科学传播 女人。为了实现这一目标，候选人将进行一个分三个阶段的计划，基于 关于一个研究要点模型，学员和她对该模型的回顾 共同导师制定了9个培训目标。这些目标规定了 从知识获取到技能发展再到综合。 拉什大学是一个有利于多学科生物医学和 临床研究项目。两位具有以病人为本专业知识的导师 结果和心血管研究(来自护理学院和 医学)将监督候选人的培训和执行 研究项目。此外，3名高级研究人员和内容专家， 在妇女和少数群体中的招募和保留领域以及 以病人为导向，将担任顾问教职员工。 这项建议的研究综合研究采用随机对照设计 调查短时间累积体力活动对血液的影响 非裔美国女性的压力[BP]和与健康相关的生活质量 高血压高危人群。这项研究不仅将影响量化 运动处方对血压和生活质量的影响，也是第一次 时间，探讨内皮功能的作用与血流动力学的相关性 在这一高危人群中BP变化的可能性。鉴于有据可查的最高 非裔美国女性肥胖率低，体力活动水平低 这些女性的运动和健康状况，以及身体状况之间的联系 活动/健身和肥胖，血压升高，易患高血压和轻度高血压 高血压的非裔美国女性是合理的体力活动对象 干预。这个项目的发现以及知识和技能 作为培训经验的一部分，将使应聘者能够 建议进行ROI级别的调查，[作为首席调查员，在 以病人为中心的多学科研究。]

DESCRIPTION: (provided by applicant) The immediate goal of this 3-year proposal is to strengthen the candidate's research knowledge and skills and provide an opportunity to synthesize these in the investigations of physical activity and other outcomes as they relate to cardiovascular disease control and prevention in women, especially those of ethnic minorities. The overall goal is to produce an independent investigator whose career commitment is to the production and dissemination of science that will make an impact on the health of minority women. To reach this goal, the candidate will pursue a 3-phase program, based on a Research Essentials model, the review of which by the trainee and her co-mentors produced 9 training objectives. These objectives provide for progression from knowledge acquisition to skill development to synthesis. Rush University is an environment conducive to multidisciplinary biomedical and clinical research projects. Two mentors with expertise in patient-oriented outcomes and cardiovascular research (from the colleges of nursing and medicine, respectively) will oversee the candidate's training and execution of the research project. In addition, 3 senior researchers and content experts, in the areas of recruitment and retention in women and minority populations and patient-oriented outcomes, will serve as consultant faculty. This propose research synthesis study uses a randomized, controlled design to investigate the impact of short bouts of accumulated physical activity on blood pressure [BP] and health-related quality of life in African-American women, a high-risk group for hypertension. This study will not only quantify the impact of exercise prescription on BP and quality of life, but also, for the first time, investigate the role of endothelial function and hemodynamic correlates of BP change in this high-risk population. Given the well documented high prevalence of obesity in African-American women, the low levels of physical activity and fitness in these same women, and the link between physical activity/fitness and obesity with elevated BP, hypertension-prone and mildly hypertensive African-American women are logical targets for a physical activity intervention. Findings from this project as well as the knowledge and skills developed as part of the training experience, will enable the candidate to propose an ROI level investigation, [as the principal investigator, in multidisciplinary patient-oriented research.]