Increasing Colon Cancer Screening in Primary Care

增加初级保健中的结肠癌筛查

• 批准号: 6331956
• 负责人: RONALD E. MYERS
• 金额: $ 72.03万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6331956
• 关键词: blood tests; books; clinical research; colon neoplasms; cost effectiveness; early diagnosis; human subject; mass screening; neoplasm /cancer diagnosis; patient care management; videotape /videodisc

ABSTRACT=The American Cancer Society recommends that men and women 50 or more years of age have a annual fecal occult blood test (FOBT) and a flexible sigmoidoscopy (FS) examination every five years to screen for colorectal cancer (CRC). Alternative CRC screening regimens that are recommended include having a barium enema X-ray (BE) at five- year intervals or a colonoscopy (CX) every 10 years. Compliance with CRC screening guidelines is low. The proposed study, Increasing Colon Cancer Screening in Primary Care, is intended to develop and test methods that may be used to increase CRC screening compliance. Study participants will be male and female patients of a large, urban primary care practice (Jefferson Family Medicine Associates), who are 50 to 74 years of age and are at average risk for CRC according to American Cancer Society guidelines. After a Baseline Survey and Baseline Chart Audit are completed, 1,488 study participants will be randomly assigned either to a Control Group, a Standard Intervention (SI) Group, a Tailored Intervention (TI) Group, or a Tailored Intervention plus Phone (TIP) Group. During a two-year period, the Control Group will receive usual care, while the intervention groups will be provided two annual screening interventions. The SI Group will receive a standard CRC screening invitation letter, a CRC screening kit (an educational booklet, and an educational videotape, and FOBTs), and a standard reminder letter. The TI Group will receive a tailored CRC screening invitation letter, a CRC screening kit, and a tailored reminder letter. Here, educational messages tailored to participant stage of decision making about screening will be embedded in the letters. The TIP Group will receive the same intervention at the TI Group, plus a tailored telephone counseling call to amplify educational messages in the tailored screening invitation letter. Midpoint and Endpoint Surveys will be administered and an Endpoint Chart Audit will be completed for study (participants. Specific aims of the study include the following: (1) Assess the impact of study interventions on screening compliance. (2) Assess the impact of study interventions on screening decision-making stage. (3) Assess the impact of study interventions on defined cognitive and psychosocial variables. (4) Identify variables associated with screening compliance and decision-making stage. (5) Evaluate intervention cost- effectiveness relative to screening compliance.

摘要=美国癌症协会建议50岁或以上的男性和女性每年进行一次粪便潜血试验（FOBT），每五年进行一次乙状结肠镜检查（FS），以筛查结直肠癌（CRC）。推荐的替代CRC筛查方案包括每隔5年进行一次钡灌肠X射线（BE）或每10年进行一次结肠镜检查（CX）。对CRC筛查指南的依从性很低。拟议的研究，增加结肠癌筛查在初级保健，旨在开发和测试方法，可用于增加CRC筛查的依从性。研究参与者将是大型城市初级保健实践（杰斐逊家庭医学协会）的男性和女性患者，年龄在50至74岁之间，根据美国癌症协会指南，CRC的平均风险。基线调查和基线图表审核完成后，1，488名研究参与者将被随机分配到对照组、标准干预（SI）组、定制干预（TI）组或定制干预加电话（TIP）组。在两年的时间里，对照组将接受常规护理，而干预组将每年接受两次筛查干预。圣莱科特国际集团将收到一封标准的CRC筛查邀请函、一套CRC筛查工具（一本教育手册、一盘教育录像带和FOBT）和一封标准的提醒函。TI集团将收到一封量身定制的CRC筛查邀请信、一个CRC筛查试剂盒和一封量身定制的提醒信。在这里，针对参与者关于筛选的决策阶段的教育信息将嵌入信件中。TIP组将接受TI组的相同干预，外加一个量身定制的电话咨询，以放大量身定制的筛选邀请函中的教育信息。将进行中点和终点调查，并完成研究（受试者）的终点图表稽查。 本研究的具体目的包括：（1）评估研究干预措施对筛查依从性的影响。(2)评估研究干预对筛选决策阶段的影响。(3)评估研究干预对定义的认知和心理社会变量的影响。(4)识别与筛选依从性和决策阶段相关的变量。(5)评估干预的成本效益相对于筛查依从性.