Unsteady Aerodynamics and Acoustics for Practical Biological Applications.

用于实际生物应用的非定常空气动力学和声学。

• 批准号: 1779588
• 金额: --
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1779588
• 关键词: Unsteady; Aerodynamics; Acoustics; Practical; Biological

Aerodynamics and Acoustics are mature fields, but their application to practical biological applications has been limited and is a high impact area for future research. In particular the fluid dynamics and aerodynamics of flows within the human body, and the mechanisms by which these flows generate and propagate sound is an open question. Understanding these flows, the generation of sounds and the nonlinear systems that govern the propagation of these sounds through human tissue is the first aim of this research project. This will involve analytical and numerical modelling as well as experiments performed in collaboration with hospitals. The second and ultimate aim is to use an improved understanding of the above-described systems to develop the modern equivalent of a stethoscope, a device that revolutionised clinical medicine when it was introduced 200 years ago. The development of this clinical technology will require not only an improved understanding of the physics of the systems, but also engineering design to develop a device that employs sensors and instrumentation, machine learning and physical insight into a clinical technology that will be present cheap and readily available alternative to other medical imaging techniques.

空气动力学和声学是成熟的领域，但它们在实际生物学应用中的应用有限，是未来研究的一个高影响力领域。特别是人体内流动的流体动力学和空气动力学，以及这些流动产生和传播声音的机制是一个悬而未决的问题。了解这些流动，声音的产生以及控制这些声音通过人体组织传播的非线性系统是本研究项目的首要目标。这将涉及分析和数字建模以及与医院合作进行的实验。第二个也是最终的目标是利用对上述系统的更好理解来开发听诊器的现代等价物，这是一种在200年前推出时彻底改变了临床医学的设备。这种临床技术的发展不仅需要更好地理解系统的物理特性，还需要工程设计来开发一种采用传感器和仪器的设备，机器学习和对临床技术的物理洞察力，这种技术将成为其他医学成像技术的廉价和现成的替代品。

项目成果

Stethoscope acoustics

听诊器声学

• DOI: 10.1016/j.jsv.2022.117194
• 发表时间: 2022
• 期刊: Journal of Sound and Vibration
• 影响因子: 4.7
• 作者: Nussbaumer M