Immunity to multiple pathogens: identification of a fungal immune receptor in barley to ascomycete and basidiomycete fungi

对多种病原体的免疫：鉴定大麦中针对子囊菌和担子菌的真菌免疫受体

• 批准号: 1786354
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1786354
• 关键词: Immunity; multiple; pathogens; identification; fungal

The majority of plants are resistant to the majority of pathogens that exist in nature. In contrast, it is the minority of interactions that permit lifecycle completion of the pathogen. The proclivity of nonhost resistance to the majority of pathogens suggests plants have a substantial capacity to resist various pathogens and/or that pathogens must make crucial adaptations to proliferate on a plant species. We have identified a resistance locus that conditions resistance to the ascomycete and basidiomycete fungi Magnaporthe oryzae and Puccinia striiformis f. sp. tritici. These two pathogens cause significant impact on global wheat and rice production, and the possibility that the same immune receptor conditions multiple pathogen recognition has profound implications in plant pathology. The project will involve the isolation of the fungal immune receptor through a combination of map-based cloning, association genetics, and bioinformatics.

大多数植物对自然界中存在的大多数病原体具有抗性。相反，只有少数相互作用才能使病原体完成生命周期。非寄主对大多数病原体的抗性倾向表明，植物具有抵抗各种病原体的强大能力，并且/或者病原体必须做出关键的适应才能在植物物种上增殖。我们已经确定了一个抗性位点，该抗性位点对子囊菌和担子菌真菌Magnaporthe oryzae和小麦条锈菌（Puccinia striiformis f. sp. tritici）产生抗性。这两种病原体对全球小麦和水稻生产产生重大影响，同一免疫受体条件下多种病原体识别的可能性在植物病理学中具有深远的意义。该项目将包括通过结合基于图谱的克隆、关联遗传学和生物信息学分离真菌免疫受体。