PROMOTING EXERCISE, SLEEP AND WELL BEING IN OLDER ADULTS

促进老年人锻炼、睡眠和健康

• 批准号: 6392405
• 负责人: ABBY C KING
• 金额: $ 74.4万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-15 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6392405
• 关键词: anxiety; body physical activity; clinical research; clinical trials; depression; exercise; health behavior; human middle age (35-64); human old age (65+); human subject; human therapy evaluation; lifestyle; longitudinal human study; personal log /diary; polysomnography; quality of life; sedative /hypnotic; sleep; sleep disorders; social psychology; stress

Sleep complaints are one of the most common health problems facing middle- and older-aged adults, resulting in significant medical utilization along with reduced psychological well-being and quality of life. In light of the cost and potential adverse effects accompanying long-term use of sedative-hypnotic medications, the development of alternative strategies for improving sleep in older populations is strongly indicated. One such potentially efficacious strategy is regular physical activity, a health behavior that typically diminishes with age. Although results from the first randomized, controlled trial evaluating the effects of increases in physical activity on sleep quality among healthy older adults with initial sleep complaints were promising, the study suffered from several methodological constraints that require further investigation. The objectives of this study are to: (1) determine the initial (6 months) and longer-term (12 months) effectiveness of a moderate-intensity physical activity program in promoting significant improvements in subjectively and objectively measured sleep quality in older adults with moderate sleep complaints; (2) evaluate the efficacy of the physical activity regimen for promoting initial and longer-term changes in a broad array of psychological and physical functioning (quality of life) variables; and (3) investigate a selected set of potential mediators and moderators of the physical activity/sleep relationship. The study design is a one-year randomized trial in which 120 sedentary women and men ages 55 years and older with moderate sleep complaints will be randomly assigned to one of two conditions: moderate-intensity physical activity training, or an attention-control (health education) condition. Both programs are designed to enhance long-term participation. Data will be collected at baseline and at 6 and 12 months using age-relevant physical performance and physical activity instruments, self-rated and objective sleep quality measures collected in the natural environment, and a comprehensive set of psychological and physical functioning scales. Our primary hypotheses are that subjects assigned to physical activity training will demonstrate significant increases in sleep quality along with other quality of life measures, maintained through 12 months, relative to the non-exercise control condition. This study will contribute important information with respect to the development of effective nonpharmacologic approaches to improving sleep quality among the large segment of healthy, community-dwelling older adults with sleep complaints.

睡眠抱怨是中老年人面临的最常见的健康问题之一，导致大量的医疗使用以及心理健康和生活质量的降低。鉴于长期使用镇静催眠药物的成本和潜在的不良影响，强烈建议开发改善老年人睡眠的替代策略。其中一个潜在的有效策略是有规律的体育活动，这种健康行为通常会随着年龄的增长而减少。尽管第一项随机对照试验的结果显示，增加体育活动对有睡眠问题的健康老年人睡眠质量的影响是有希望的，但该研究存在一些方法学上的限制，需要进一步调查。本研究的目的是：(1)确定中等强度体育活动计划在促进有中度睡眠抱怨的老年人主观和客观测量的睡眠质量显著改善方面的初始（6个月）和长期（12个月）的有效性；(2)评估体育锻炼方案在促进一系列心理和身体功能（生活质量）变量的初始和长期变化方面的功效；(3)研究身体活动/睡眠关系的潜在中介和调节因子。研究设计是一项为期一年的随机试验，其中120名55岁及以上的久坐不动的女性和男性，有中度睡眠问题，将被随机分配到两种情况中的一种：中等强度的体育活动训练，或注意力控制（健康教育）条件。这两个项目都旨在促进长期参与。数据将在基线和6个月和12个月时收集，使用与年龄相关的身体表现和身体活动仪器，在自然环境中收集的自评和客观睡眠质量测量，以及一套综合的心理和身体功能量表。我们的主要假设是，与非运动控制条件相比，分配到体育锻炼训练的受试者将表现出睡眠质量和其他生活质量指标的显著提高，并维持12个月。本研究将为开发有效的非药物方法来改善大部分健康的、社区居住的有睡眠问题的老年人的睡眠质量提供重要信息。