FIBER OPTIC ENDODONTIC MICRO-PROBE FOR ROOT CANAL

根管用光纤根管显微探针

• 批准号: 6292532
• 负责人: Srivatsa Venkatasubbarao
• 金额: $ 8.64万
• 依托单位: INTELLIGENT OPTICAL SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-20 至 2002-03-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6292532
• 关键词: X ray spectrometry; biomedical equipment development; dental structure; diagnosis design /evaluation; endodontics; fiber optics; fluorescent dye /probe; histology; human tissue; root canal therapy; scanning electron microscopy; surgery material /equipment

Intelligent Optical Systems Inc.(IOS), in collaboration with the Beckman Laser Institute (BLI) of the University of California Irvine, proposes to develop an innovative fiber optic endodontic microprobe for root canal diagnosis. The proposed device, packaged to match the shape, weight, and balance of current passive Dental probes, will excite and collect endodontic fluorescence using a rugged and flexible optical fiber packaged in a stainless steel tube. In Phase 1, IOS, in collaboration with Dr. Petra Wilder-Smith, Director of the Dental Program at BLI, will conduct in-vitro investigations of quantitative fluorescence activity in freshly extracted human teeth/pulps/alveolar bone, with fully documented in vivo clinical and radiographic diagnosis of each. Histology, light microscopy, and scanning electron microscopy (SEM) combined with energy dispersive x-ray (EDX) spectroscopy will be performed on these specimens as appropriate to establish the exact health status of each tissue sample. The results will be compared with the fluorescence spectra collected from each sample. PROPOSED COMMERCIAL APPLICATION: Not available

智能光学系统公司（IOS）与 加州大学欧文分校贝克曼激光研究所 (BLI) 提出 开发一种创新的根管光纤牙髓微探针 诊断。所提议的设备，包装以匹配形状、重量和 当前被动牙科探针的平衡，将激发和收集牙髓 使用封装在不锈钢中的坚固且灵活的光纤发出荧光 钢管。在第一阶段，IOS 与 Petra Wilder-Smith 博士合作， BLI 牙科项目主任将进行体外研究 新鲜提取的人体中的定量荧光活性 牙齿/牙髓/牙槽骨，具有完整的体内临床和记录记录 每个的放射线诊断。组织学、光学显微镜和扫描 电子显微镜 (SEM) 与能量色散 X 射线 (EDX) 相结合 将对这些样本进行适当的光谱分析以确定 每个组织样本的确切健康状况。将比较结果 从每个样品收集的荧光光谱。 拟议的商业应用： 无法使用