MOLECULAR GENETICS OF PREECLAMPSIA/ECLAMPSIA

先兆子痫/子痫的分子遗传学

• 批准号: 6304856
• 负责人: ROGER A WILLIAMSON
• 金额: $ 2.2万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6304856
• 关键词: chromosomes; clinical research; eclampsia; female; gene expression; genetic mapping; human subject; molecular genetics; pathologic process; preeclampsia; pregnancy disorder; women's health

The goals of this study are to elucidate the genetic importance of leading candidate genes in the pathogenesis of preeclampsia/eclampsia, conduct a genome-wide search for chromosomal regions that may be linked to preeclampsia, and identify and evaluate candidate genes within the linked chromosomal regions in women who have had a previous pregnancy complicated by preeclampsia or eclampsia.

这项研究的目标是阐明领先的候选基因在先兆子痫/子痫的发病机理中的遗传重要性，对染色体区域进行染色体区域进行搜索，这些染色体区域可能与先兆子痫有关，并通过先前患有孕妇或ececectsececectectsecection的女性中的候选基因识别和评估候选基因。