CORE--MOLECULAR/ANIMAL

核心--分子/动物

• 批准号: 6300914
• 负责人: ROGER A WILLIAMSON
• 金额: $ 13.54万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6300914
• 关键词: animal colony; biomedical facility; gene targeting; genetically modified animals; genotype; laboratory mouse; nucleic acid sequence

The Molecular/Animal Core will have the primary mission of providing core resources to individual projects that will involve the generation of transgenic animals and their characterization, as well as genotyping and DNA sequence analysis. A secondary aim will be to provide training opportunities in transgenic animal work and/or molecular analysis for either established investigators moving into these areas or as opportunities for junior investigators with prior experience to develop these abilities. The overall core is directed by Dr. Roger Williamson, who currently serves as Director of the Transgenic Core Facilities on the campus at the University of Iowa and who in the last three years has developed substantial expertise in transgenic animal work associated with craniofacial anomalies. Dr. Murray will serve as co-director and oversee activities related to genotyping and DNA sequencing. The core will be supported by research scientists and technicians who already have long-standing expertise in the technical aspects of the work that they will be supporting. Facilities will be house in standing expertise in the technical aspects of the work that they will be supporting. Facilities will be house in existing molecular biology and animal units and will provide for a seamless transition of data and technology for both on-campus and off-campus projects. The core will provide direction and support to all Projects and both pilot projects.

分子/动物核心将其主要使命是为各个项目提供核心资源，这些项目将涉及转基因动物的产生及其表征，以及基因分型和DNA序列分析。第二个目的是为既定的研究人员搬进这些领域的成熟动物工作和/或分子分析提供培训机会，或者作为具有先前经验的初级调查人员发展这些能力的机会。总体核心是由罗杰·威廉姆森（Roger Williamson）博士指导的，罗杰·威廉姆森（Roger Williamson）目前担任爱荷华大学校园的转基因核心设施主任，并且在过去三年中，他在与颅面异常相关的转基因动物工作方面发展了丰富的专业知识。 Murray博士将担任与基因分型和DNA测序有关的共同导演，并监督活动。核心将得到研究科学家和技术人员的支持，他们已经在他们将支持的工作的技术方面拥有长期的专业知识。设施将成为他们将支持的工作技术方面的常规专业知识。设施将成为现有的分子生物学和动物单元的房屋，并为校园和校外项目提供无缝的数据和技术过渡。核心将为所有项目和两个试点项目提供指导和支持。