PLASMA & ERYTHROCYTE FATTY ACIDS IN TREATED CHILDREN W/ PKU

本研究旨在验证以下假设：1)服用不同医疗食品的PKU儿童与正常儿童之间的必需脂肪酸摄入量没有差异；2)接受不同医疗食品治疗的PKU儿童与正常儿童之间的血浆和红细胞脂肪酸水平没有差异。研究人员将对正在接受PKU治疗的儿童的全民教育摄入量与他们正常兄弟姐妹的摄入量进行比较。这些儿童服用的是洛芬那酸、苯奈克斯、不含苯丙酚或XP的Maximaid。正在接受PKU治疗的儿童的血浆和红细胞脂肪酸谱将与他们正常兄弟姐妹的脂肪酸谱进行比较，这些儿童正在服用洛芬那酸、苯尼司、不含苯酚或XP的Maxamaid。

This proposal is designed to test the hypotheses that: 1) there are no differences in the intake of essential fatty acids (EFAS) among groups of children with PKU fed different medical foods and normal children, and 2) there are no differences in the plasma and erythrocyte fatty acids among groups of children undergoing therapy for PKU with different medical foods and normal children. The investigators will compare EFA intake of children undergoing therapy for PKU who are ingesting Lofenalac, Phenex, Phenyl-free or XP Maximaid to intakes of their normal siblings. Plasma and erythrocyte fatty acid profiles of children undergoing therapy for PKU who are ingesting Lofenalac, Phenex, Phenyl-free, or XP Maxamaid will be compared to the fatty acid profiles of their normal siblings.