Do False Positive Mammograms Negatively Effect Health?

描述(应用后)：虽然筛查乳房X光检查是清楚的 有利于降低乳腺癌死亡率，乳房X光检查假阳性 结果很常见，估计累积风险约为50% 经过10年的年度筛查后，这一比例为10%。几项研究表明， 假阳性乳房X光检查会导致不良的心理和社会问题 效果。这些影响对一些女性来说可能是相当大的， 影响日常运作。这样的患者可能正在经历一种标签 像以前在新诊断的高血压患者中描述的现象 病人。对这些问题的更好理解将有助于发展 减少筛查乳房X光检查的不良影响的策略 确定可能不建议进行乳房X光检查的人群。 这个项目的目的是分析两个已建立的基于人口的 数据库以确定是否存在此类标注效果 假阳性乳房X光检查。具体目标是： 1.确定接受过筛查乳房X光检查的妇女人数 并可前瞻性地跟踪至少一年，并对其进行分类 这些妇女根据假阳性或真阴性乳房X光检查的状况。 2.比较两组女性，乳房X光检查假阳性和 那些乳房X光检查为真阴性的人，在一年结束时 休息日、感觉到的健康状况、医生就诊和医疗 支出。 3.对结果进行二次分析，查看与 种族、年龄、社会经济地位和合并症。 队列将独立于医疗支出小组建立 调查(MEP)和监测的无癌对照组 流行病学和最终结果(SEER)/医疗保险相关数据库(SEER 控制)。休假工作天数、感知的健康状态和利用率 使用MEPS患者进行评估。更详细的医疗保健利用率和 将使用SEER进行种族/社会经济分组分析 控制。

DESCRIPTION (after the application): Although screening mammography is clearly beneficial in reducing breast cancer mortality, false positive mammogram results are common, with an estimated cumulative risk of approximately 50 percent after 10 years of annual screening. Several studies suggest that false positive mammograms can lead to adverse psychological and social effects. These effects may be substantial enough in some women to negatively effect daily functioning. Such patients may be experiencing a labeling phenomenon such as that described previously in newly diagnosed hypertensive patients. Better understanding of these issues would permit the development of strategies for reducing the adverse effects of screening mammography or the identification of populations for whom mammography might not be advised. The purpose of this project is to analyze two established population-based databases to determine whether such a labeling effect is present following a false positive mammogram. The specific aims will be: 1. To identify a population of women that has undergone screening mammography and can be followed prospectively for at least one year, and to categorize these women according to false positive or true negative mammogram status. 2. To compare two groups of women, those with false positive mammograms and those with true negative mammograms, at the end of one year with regard to days-off work, perceived health status, physician visits and medical expenditures. 3. To perform secondary analyses of the outcomes looking at associations with race, age, socioeconomic status, and comorbidity. Cohorts will be constructed independently from the Medical Expenditure Panel Survey (MEPS) and the cancer-free control group of the Surveillance Epidemiology and End Results (SEER) /Medicare-linked databases.(SEER Controls). Days-off work, perceived health status, and utilization will be evaluated using the MEPS patients. More detailed health care utilization and race/ socioeconomic subgroup analysis will be conducted using the SEER controls.