Do False Positive Mammograms Negatively Effect Health?

乳房X光检查假阳性会对健康产生负面影响吗？

• 批准号: 6666762
• 负责人: GEOFFREY C LAMB
• 金额: $ 4.92万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2005-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6666762
• 关键词: anxiety; attitude; behavioral /social science research tag; clinical research; diagnosis quality /standard; female; health behavior; health care service utilization; health services research tag; human data; mammography; psychological aspect of cancer

DESCRIPTION (after the application): Although screening mammography is clearly beneficial in reducing breast cancer mortality, false positive mammogram results are common, with an estimated cumulative risk of approximately 50 percent after 10 years of annual screening. Several studies suggest that false positive mammograms can lead to adverse psychological and social effects. These effects may be substantial enough in some women to negatively effect daily functioning. Such patients may be experiencing a labeling phenomenon such as that described previously in newly diagnosed hypertensive patients. Better understanding of these issues would permit the development of strategies for reducing the adverse effects of screening mammography or the identification of populations for whom mammography might not be advised. The purpose of this project is to analyze two established population-based databases to determine whether such a labeling effect is present following a false positive mammogram. The specific aims will be: 1. To identify a population of women that has undergone screening mammography and can be followed prospectively for at least one year, and to categorize these women according to false positive or true negative mammogram status. 2. To compare two groups of women, those with false positive mammograms and those with true negative mammograms, at the end of one year with regard to days-off work, perceived health status, physician visits and medical expenditures. 3. To perform secondary analyses of the outcomes looking at associations with race, age, socioeconomic status, and comorbidity. Cohorts will be constructed independently from the Medical Expenditure Panel Survey (MEPS) and the cancer-free control group of the Surveillance Epidemiology and End Results (SEER) /Medicare-linked databases.(SEER Controls). Days-off work, perceived health status, and utilization will be evaluated using the MEPS patients. More detailed health care utilization and race/ socioeconomic subgroup analysis will be conducted using the SEER controls.

描述（应用后）：虽然筛查乳房X线摄影明显 有利于降低乳腺癌死亡率，假阳性乳房X线检查 结果是常见的，估计累积风险约为50 每年筛查10年后，一些研究表明 假阳性的乳房X光检查会导致不良的心理和社会影响， 方面的影响.这些影响可能是实质性的，足以在一些妇女， 影响日常运作。这些患者可能正在经历一个标签 如先前在新诊断的高血压患者中描述的现象 患者更好地了解这些问题将有助于发展 减少筛查性乳房X光检查或 确定可能不建议进行乳房X光检查的人群。 本项目的目的是分析两个已建立的基于人口的 数据库，以确定是否存在这样的标记效应之后， 假阳性乳房X光片具体目标是： 1.确定接受筛查性乳腺X线摄影的女性人群 并且可以前瞻性地随访至少一年， 这些妇女根据假阳性或真阴性乳房X光检查状态。 2.为了比较两组妇女，那些假阳性乳房X光检查和 那些乳房X光检查结果为真阴性的人，在一年底， 休息日工作，自觉健康状况，医生访问和医疗 支出。 3.对结局进行二次分析，观察与以下因素的关联： 种族、年龄、社会经济地位和科摩罗。 队列将独立于医疗支出小组构建 调查（MEPS）和监测的无癌对照组 流行病学和最终结果（SEER）/Medicare相关数据库。（SEER 对照）。休息日的工作，感知的健康状况，和利用将是 使用MEPS患者进行评估。更详细的医疗保健利用和 将使用SEER进行种族/社会经济亚组分析 对照