HEART DIS & COPD: EXERCISE METAB & OXYGEN DELIVERY IN HEALTH & DISEASE
HEART DIS & COPD: EXERCISE METAB & OXYGEN DELIVERY IN HEALTH & DISEASE
批准号:
6495475
负责人:
ELIZABETH A NOYSZEWSKI
金额:
$22.55万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-09-01 至 2002-08-31
中文摘要
针灸是中国传统文化的重要组成部分
医药。它在中国身上已经流传了数千年,作为
部分治疗针对不同的医疗条件。它正在逐渐地
被西方国家接受为一种缓解疼痛和
用于治疗其他疾病。此外,还有更多和
关于针刺对人体生理影响的更多研究
身体。
这项研究是对物理效应的探索
针对人类的针灸疗法。使用磁共振成像和
光谱技术(MRI和MRS),我们将检查信号变化,
如果有的话,在大脑活动和身体新陈代谢方面
针灸刺激。我们假设针灸疗法
将改变血流模式和代谢率。
我们一直在测试血液流动的适用性
量化技术对这项研究的影响,特别是在它们
使我们能够识别针灸引起的脑功能变化
大脑、骨骼肌和内脏器官。使用功能磁共振成像,我们将
比较前、中、后的脑激活模式
针灸治疗。我们还将从控制组生成数据
未接受针灸治疗的受试者。
我们用流量量化的方法进行了两个案例研究。一
观察针刺足三里穴治疗慢性阻塞性肺疾病的疗效。
用2D-闪光血流敏感序列测量腿部血流量。这个
另一项是用类似的序列来观察针灸
会影响门静脉和肾动脉的血流。那里
是针灸引起血流变化的指征。然而,更多
需要对受试者进行研究才能得出决定性的结果。
英文摘要
Acupuncture is a significant component of traditional Chinese
medicine. It has been practiced in China for thousands of years as
part of the treatment for diverse medical conditions. It is gradually
becoming accepted in Western countries as a method of pain relief and
in the treatment of other diseases. In addition, there is more and
more research into the physiological effects of acupuncture on human
bodies.
This study is an exploration of the physical effects of
acupuncture on humans. Using magnetic resonance imaging and
spectroscopic techniques (MRI & MRS), we will examine signal changes,
if any, in cerebral activity and body metabolism in response to
acupuncture stimulation. We hypothesize that acupuncture treatment
will modify blood flow patterns and metabolic rates.
We have been testing the applicability of blood flow
quantification techniques to this study, particularly insofar as they
enable us to identify the functional changes induced by acupuncture in
the brain, skeletal muscle and visceral organs. Using fMRI, we will
compare the brain activation pattern before, during, and after
acupuncture treatment. We will also generate data from control group
of subjects not treated with acupuncture.
We did two case studies with flow quantification method. One
case was to observe the effects of acupuncture at acupoints St36 on
leg blood flow quantified with 2D-flash flow sensitive sequence. The
other one was, using the similar sequence, to observe how acupunture
would influence the flow of portal vein and kidney arteries. There
are indication of flow change induced by acupuncture. However, more
subjects need to be studied for conclusive results.
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HEART DIS & COPD: EXERCISE METAB & OXYGEN DELIVERY IN HEALTH & DISEASE
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批准号:6657666
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项目类别:
-
资助金额:$22.55万
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财政年份:2002
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:
HEART DIS & COPD: EXERCISE METAB & OXYGEN DELIVERY IN HEALTH & DISEASE
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批准号:6349332
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项目类别:
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资助金额:$5.6万
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财政年份:2000
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:
EXERCISE METABOLISM & OXYGEN DELIVERY IN CHRONIC RENAL FAILURE
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批准号:6121069
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项目类别:
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资助金额:$1.35万
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财政年份:1998
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:
EXERCISE METABOLISM & OXYGEN DELIVERY IN CHRONIC RENAL FAILURE
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批准号:6252182
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项目类别:
-
资助金额:$1.94万
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财政年份:1997
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:
CLINICAL APPLICATION OF DEOXYMYOGLOBIN TECHNIQUE: PERIPHERAL VASCULAR DIS OR CFS
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批准号:5224011
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:--
MAGNETIC RESONANCE SPECTROSCOPY OF NORMAL BREAST TISSUE AT 4 TESLA
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批准号:5224028
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:ELIZABETH A NOYSZEWSKI
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依托单位:--
THEORETICAL ANALYSIS OF OXYGEN DELIVERY TO TISSUE: STROKE OR VASCULAR DIS
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批准号:5224015
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项目类别:
-
资助金额:$0.0万
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财政年份:--
-
负责人:ELIZABETH A NOYSZEWSKI
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依托单位:--