课题基金 / 基金详情

CAUSES AND MANAGEMENT OF PRIMARY HYPERCHOLESTEROLEMIA

CAUSES AND MANAGEMENT OF PRIMARY HYPERCHOLESTEROLEMIA
原发性高胆固醇血症的原因和治疗
批准号：
6414489
负责人：
Scott M. Grundy
金额：
$32.14万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-12-01 至 2001-11-30
来源：
https://reporter.nih.gov/project-details/6414489
关键词：
antihyperlipoproteinemic agent blood disorder chemotherapy blood lipoprotein metabolism clinical research combination therapy diet therapy dietary lipid drug adverse effect drug screening /evaluation human subject human therapy evaluation hypercholesterolemia low density lipoprotein metabolism disorder chemotherapy nutrition related tag very low density lipoprotein

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中文摘要
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英文摘要
This NIH project examines lipoprotein defects, evaluates clinical significance and the need to treat. Treatment options under investigation include role of individual dietary fatty acids and the mode of action, safety and efficacy of single and combined drug therapy. Metabolic unit studies are conducted as well as kinetic studies. Metabolism and underlying defects in lipoproteins are being minutely analysed. Source of research material is plasma lipoproteins throughout the different study phases. LDL/VLDL turnover studies will be utilized.
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