HOUSE DUST MITE ANTIGEN ON SKIN OF PATIENTS WITH ATOPIC DERMATITIS

特应性皮炎患者皮肤上的屋尘螨抗原

• 批准号: 6307457
• 负责人: THOMAS A. PLATTS-MILLS
• 金额: $ 2.81万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6307457
• 关键词: allergens; atopic dermatitis; clinical research; clinical trials; controlled environment; dust; eczema; human subject; immunoglobulin E; immunoglobulin genes; mites

Patients with eczema and elevated IgE antibodies to house dust mites will be admitted to a "mite free" environment. After significant improvement of their skin, they will be exposed to either active or placebo dust double blind. Both patient and physician will score the skin involvement daily and skin scales will be vacuumed from sheets daily for quauntitation of IgG.

湿疹和室内尘螨IgE抗体升高的患者将被允许进入“无螨”环境。 在他们的皮肤显著改善后，他们将暴露于活性或安慰剂粉尘双盲。 患者和医生将每天对皮肤受累进行评分，并每天从床单上吸尘皮肤鳞片，以定量IgG。