STRUCTURE OF BIOMACROMOLECULAR FUNCTION & ACTIVITY

生物大分子功能结构

• 批准号: 6422170
• 负责人: YUN WANG
• 金额: --
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6422170
• 关键词: RNA binding protein; biochemistry; biophysics; drug design /synthesis /production; enzyme complex; macromolecule; nuclear magnetic resonance spectroscopy; nucleic acids; protein structure function; structural biology

The general research interests of our group are to determine the structure of biological molecules, including nucleic acids, enzymes, RNA(DNA)protein complexes and clinically important enzyme drug complexes, using NMR and various other biophysical and biochemical methods. The knowledge of these biological structures will help us to understand the structural basis for the function of biological molecules and complexes.

我们小组的总体研究兴趣是利用核磁共振和各种其他生物物理和生化方法确定生物分子的结构，包括核酸，酶，RNA（DNA）蛋白质复合物和临床重要的酶药物复合物。这些生物结构的知识将帮助我们了解生物分子和复合物功能的结构基础。