MIDARP AT HUNTER COLLEGE

纽约城市大学亨特学院的少数民族人口传统上很高（超过50%）。我们的目标是在亨特大学开发一个项目，利用现有的优势，扩大和鼓励亨特大学的药物滥用研究。这个药物滥用研究项目将包括对不同药物滥用反应的分子、细胞和行为水平的研究。它将包括活跃的研究人员，研究生和本科生的研究生，以及心理和生物系的技术支持人员，他们对将成瘾理解为一种脑部疾病有共同的兴趣，或者希望将他们的研究工作推向这个方向。提案的目的是加强亨特的研究基础设施，以促进我们在药物滥用研究方面的努力，在我们的部门内开发该研究领域的个人项目，并激发其他教师和学生（包括本科生和研究生）对药物滥用研究的兴趣。该中心的一个整体目标是促进少数民族本科生和研究生的职业发展，他们将成为未来的独立科学家。提出的具体项目包括：1)甲基苯丙胺致敏机制；2)药物成瘾与冲动行为的神经生物学；3)应激与精神兴奋剂药物对行为敏感性和记忆的相互作用；4)发情周期和性别差异对可卡因诱导中枢神经系统改变的影响。没有提交研究项目的PI是一个已建立的药物滥用研究，将担任这些项目的顾问和初级科学家的导师。我们五个人中有三个是西班牙裔科学家，另外两个非少数族裔科学家在培训少数族裔学者方面有着悠久的历史，他们是COR、MARC和MBRS基金管理部门的一部分。五个项目中有三个在与新开发计划署任务一致的领域开展工作，另外两个正在朝这个方向发展。最后，我们中的两位是资深科学家，每人都有超过25年的研究经验，他们将作为这个小组中更年轻的教员的导师，尤其是今年加入亨特的两位教员。这种指导的机制是建立在我们的合作和项目本身之中的。

Hunter College of the City University of New York has a traditionally high (greater than 50 percent) minority population. It is our goal to develop a program at Hunter that draws on existing strengths to broaden and encourage drug abuse research at Hunter. This program for studies on drug abuse will encompass research on the molecular, cellular, and behavioral level in response to different drugs of abuse. It will include active research faculty, graduate and undergraduate research students, and technical support personnel in the Psychology and Biology Departments, who share an interest in understanding addiction as a brain disease or who want to move their research efforts in that direction. The aims of proposal are to enhance the research infrastructure of Hunter to facilitate our efforts in drug abuse research, develop individual projects within our departments within this area of research, and to stimulate the interest of other faculty and our students, both at the undergraduate and graduate levels, in research on drug abuse. An integral goal of this center is to facilitate the career development of minority undergraduate and graduate students who will become the independent scientists of the future. The specific projects proposed include: 1) Mechanism of sensitization to methamphetamine; 2) Neurobiology of drug addiction and impulsive behavior; 3) Interactions between stress and psychostimulant drugs in behavioral sensitivity and memory; and 4) Effects of the estrous cycle and gender differences in cocaine-induced alterations in the CNS. The PI, who is not submitting a research project is an established drug abuse research and will serve as advisor on these projects and mentor to the junior scientists. Three of the five of us are Hispanic scientists and the two non- minority scientists have a long history of training minority scholars and are part of the administration of the COR, MARC and MBRS grants. Three of the five work in areas consistent with the NIDA mission and the other two are moving in that direction. Finally, two of us are senior scientists with over 25 years of research experience each and will serve as mentors to the more junior faculty of this group, especially the two faculty who have joined Hunter this year. The mechanisms for this mentoring are built into the collaborations that we have and the program itself.