PREDOCTORAL TRAINING IN EXERCISE PHYSIOLOGY AND AGING

马里兰大学帕克分校（UMCP）运动机能系博士前运动生理学和衰老训练项目有着悠久的历史，培养了训练有素的博士毕业生，他们完成了博士后培训，成为了富有成效的学术教职员工。该计划为学员提供基本知识和经验，为他们进行高质量的博士论文研究做好准备：1)在运动生理学、心血管、代谢和衰老遗传研究方面的临床和基础实验室调查，以研究老年人心血管疾病危险因素的病理生理学；2)研究运动干预对代谢、心血管、以及老年男性和女性的肌肉骨骼功能。课程内容包括：1)老年学/老年医学的基础知识；2)运动、心血管和代谢生理学的专业知识；3)生物化学、内分泌学、遗传学、细胞生物学和其他生物科学的辅助课程；4)研究设计、生物统计学和计算机应用。UMCP培训项目的研究涉及与UM医学院（UMSM）老年学部门和nia老年学研究中心的长期密切合作。受训者在UMCP初级导师和来自UMSM、nia -老年学研究中心和匹兹堡大学公共卫生研究生院人类遗传学系的二级和副导师的指导下获得实验室和临床研究经验。课程作业和实验室经验的设计，最终在每个学员的论文研究项目。我们以前的博士学员在高水平的同行评审的临床，老年学和生理学期刊上发表了许多手稿，并在NIH博士后培训和学术教师职位上取得了进展。我们建议在这个培训项目中支持2-5名学员，每人资助4年，以提供最佳的培训体验。这种训练已经被证明，并将继续培养具有运动生理学和衰老应用于新陈代谢、肌肉骨骼和心血管生理学以及遗传学的综合知识的博士毕业生，他们将完成博士后研究，并最终成为大学和医疗中心的学术教员。

The University of Maryland College Park (UMCP) Department of Kinesiology predoctoral exercise physiology and aging training program has a long history of producing well-trained PhD graduates who completed postdoctoral training and become productive academic faculty members. The program provides trainees with the basic knowledge and experiences to prepare them for high quality dissertation research addressing 1) clinical and basic laboratory investigations in exercise physiology, cardiovascular, metabolism, and genetic aspects of aging research to study the pathophysiology of risk factors for cardiovascular disease in the elderly and 2) the study of the effects of exercise interventions on metabolic, cardiovascular, and musculoskeletal function in older men and women. The program consists of a didactic curriculum providing 1) basic knowledge in gerontology/geriatrics, 2) discipline-specific knowledge in exercise, cardiovascular, and metabolic physiology, 3) supporting courses in biochemistry, endocrinology, genetics, cell biology, and other biological sciences, and 4) research design, biostatistics, and computer applications. The research of the UMCP training program involves longstanding and close collaborations with the UM School of Medicine (UMSM) Division of Gerontology and the NIA-Gerontology Research Center. Trainees receive laboratory and clinical research experience under the guidance of primary UMCP mentors and secondary and associate mentors from UMSM, the NIA-Gerontology Research Center, and the University of Pittsburgh Graduate School of Public Health Department of Human Genetics. Coursework and laboratory experiences are designed to culminate in each trainee's dissertation research project. Our previous PhD trainees have published numerous manuscripts in high-level peer- reviewed clinical, gerontology, and physiology journals and have progressed on to NIH postdoctoral training and academic faculty positions. We propose to support 2-5 trainees in this training program with each funded for 4 years to provide an optimal training experience. Such training has already been shown, and will continue, to produce PhD graduates with an integrated knowledge of exercise physiology and aging applied to metabolism, musculoskeletal and cardiovascular physiology, and genetics who will complete postdoctoral fellowships and eventually become academic faculty members in universities and medical center.