Predoctoral Training in Exercise Physiology and Aging

描述（由申请人提供）：马里兰州大学公园（UMCP）运动生物学和衰老计划的部门有生产训练有素的博士谁完成博士后培训，并成为富有成效的学术教师的历史。该计划为研究员提供培训，使他们为高质量的论文研究做好准备，这些论文研究涉及1）运动生物学的临床和基础实验室调查（运动、心血管（CV）、肌肉骨骼和代谢生理学和遗传学）与衰老的关系，以研究老年人CV疾病、福尔斯和身体功能障碍的风险因素，2）运动干预对肌肉骨骼、代谢、和CV功能在老年人，和3）常见的遗传变异的影响，老年人的反应，运动训练。该计划的课程提供; 1）衰老的基础知识，2）运动，CV，肌肉骨骼和代谢生理学的具体知识，3）遗传学，生物化学，细胞生物学和其他生命科学课程，以及4）生物统计学和研究设计。培训计划教师的研究涉及与医学的UM学校（UMSM）老年学，肾脏病学和内分泌学，糖尿病和营养学，公共卫生（Pitt-GSPH）的匹兹堡大学研究生院的部门的长期合作，和NIA-Gerontology研究中心（NIA-GRC）。受训者获得UMCP初级导师和来自UMSM，NIAGRC和Pitt-GSPH的二级和副导师的实验室和临床研究经验。课程和实验室经验为每个研究员的论文研究提供了基础。我们之前的博士生在临床、老年学和生理学期刊上发表了大量论文，所有研究员都已继续接受NIH博士后培训和教师职位。我们建议支持5-6名研究员4年，以提供最佳的培训经验。这样的培训显然会培养出具有运动生物学和衰老综合知识的博士，他们将完成博士后研究并成为学术教师。

DESCRIPTION (provided by applicant): The University of Maryland College Park (UMCP) Department of Kinesiology exercise biology and aging program has a history of producing well-trained PhDs who complete postdoctoral training and become productive academic faculty members. The program provides fellows with the training to prepare them for high quality dissertation research addressing 1) clinical and basic laboratory investigations in exercise biology (exercise, cardiovascular (CV), musculoskeletal, and metabolic physiology and genetics) and aging to study the risk factors for CV disease, falls, and physical dysfunction in the elderly, 2) the effects of exercise interventions on musculoskeletal, metabolic, and CV function in older persons, and 3) the effects of common genetic variations on the responses of older persons to exercise training. The program's curriculum provides; 1) basic knowledge in aging, 2) specific knowledge in exercise, CV, musculoskeletal, and metabolic physiology, 3) courses in genetics, biochemistry, cell biology, and other life sciences, and 4) biostatistics and research design. The research of the Training Program faculty involves longstanding collaborations with the UM School of Medicine (UMSM) Divisions of Gerontology, Nephrology, and Endocrinology, Diabetes, and Nutrition, University of Pittsburgh Graduate School of Public Health (Pitt-GSPH), and NIA-Gerontology Research Center (NIA-GRC). Trainees receive laboratory and clinical research experience with UMCP Primary Mentors and Secondary and Associate Mentors from UMSM, NIAGRC, and Pitt-GSPH. Coursework and laboratory experiences provide the basis for each fellow's dissertation research. Our previous PhD trainees have published numerous papers in clinical, gerontology, and physiology journals, and all fellows have gone on to NIH postdoctoral training and faculty positions. We propose to support 5-6 fellows for 4 yrs to provide an optimal training experience. Such training clearly produces PhDs with an integrated knowledge of exercise biology and aging that will complete postdoctoral fellowships and become academic faculty members.