TRAINING IN IMMUNODERMATOLOGY

描述(申请人提供)：大卫·诺里斯医学博士将成为私家侦探 现任培训联席主任威廉·韦斯顿医学博士担任高级顾问 角色。诺里斯博士将继续开发协作互动 对未来的这笔机构培训拨款至关重要。在过去的三年里 培训期26名毕业生中有24人进入全日制学术生涯，18人 目前都保留在全日制皮肤科学术研究。还有一个人还在 训练。培训人员将扩大到9名医学博士和3名博士 教职员工将包括更多资深科学家，包括细胞和 结构生物学，丹佛自体免疫中心主任和 人类医学遗传学负责人、《过敏杂志》现任主编 和临床免疫学。本部门前见习主管 免疫学、药理学和风湿病医学部 包括医学系的肿瘤学和传染病。 培训教员每人都有独立的资金(2001-02年为1540万美元， 并且每个人都成功地指导了过去的实习生 学术生涯。感兴趣的领域包括：皮肤分子 病毒学、黑素细胞生物学、分子遗传学、黑色素瘤、非黑色素瘤皮肤 癌症、癌基因、细胞毒性机制和程序性细胞死亡， 白三烯，包括IL-1在内的细胞因子，T细胞受体，光免疫学，细胞 信号和细胞表面受体。可用的设施和设备 实习生已升级。到2003年，实习生将搬到新大学 科罗拉多州癌症研究大楼有超过7000个潮湿的实验室空间 可用于计划的皮肤科部分，与立即相邻 在癌症中心。 建议博士和医学博士候选人都包括在两个 每年招募受训人员。所有实习生都应该证明他们是 能够从事皮肤病学或皮肤生物学的学术研究。四 提出了培训的要点：正式课程工作、研讨会、个人 研究项目和沟通技能培训。特别强调 免疫学、分子生物学、分子遗传学、 细胞生物学、科学伦理学、生物统计学与危险物质管理 提出了浪费的建议。学员将选择自己感兴趣的项目或从 在培训监督员提供给他们的一份广泛的名单中。沟通 学员的技能将得到强调，并将接受科学技术方面的专门培训 由Lee&Weston博士指导的写作和演讲。

DESCRIPTION (provided by applicant): David Norris M.D. will become the PI with the current training Co-director, William Weston M.D. assuming a senior advisor role. Dr. Norris will continue to develop the collaborative interactions critical to this institutional training grant in the future. In the past three training periods 24 of 26 graduates entered full time academic careers and 18 are currently retained in full time academic dermatology. There is one still in training. The training faculty will be enlarged to 9 M.D. & 3 Ph.D. training faculty to include more senior scientists including the Chairman of Cell and Structural Biology, the Director of the Denver Autoinimunity Center and the Head of Human Medical Genetics and the current Editor of the Journal of Allergy and Clinical Immunology. Previous trainee supervisors in the Department of Immunology, the Department of Pharmacology & Divisions of Rheumatology, Medical Oncology and Infectious Diseases of the Department of Medicine are included. The training faculty each have independent funding ($15.4 million for 2001-02, and have each demonstrated successful mentoring of past trainees leading to academic careers. Research areas of interest include: cutaneous molecular virology, melanocyte biology, molecular genetics, melanoma, nonmelanoma skin cancer, oncogenes, cytotoxic mechanisms and programmed cell death, leukotrienes, cytokines including IL1, T cell receptors, photoimmunology, cell signaling and cell surface receptors. Facilities and equipment available to trainees have been upgraded. By 2003, trainees will move to the new University of Colorado Cancer research building with over 7,000 of wet laboratory space available for the dermatology portion of the program with immediate adjacency within the Cancer Center. It is proposed that both Ph.D. and M.D. candidates be included with two trainees recruited each year. All trainees should have demonstrated they are capable of a career in academic dermatology or cutaneous biology. Four essentials of training are proposed: Formal course work, seminars, individual research projects and training in communications skills. Special emphasis on formal coursework in Immunology, Molecular Biology, Molecular Genetics, Cellular Biology, Scientific Ethics, Biostatistics and Management of Hazardous waste is proposed. Trainees will select a project of their own interest or from among a broad list presented to them by the training supervisors. Communication skills of the trainees will be emphasized with specific training in scientific writing and presentations supervised by Drs. Lee & Weston.