New Generation of Opto-Electronic Patch Sensor to enable effective human vital signs monitoring for healthcare, personal health monitoring during phys
新一代光电贴片传感器可实现有效的人体生命体征监测,用于医疗保健、理疗期间的个人健康监测
基本信息
- 批准号:1838849
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:英国
- 项目类别:Studentship
- 财政年份:2017
- 资助国家:英国
- 起止时间:2017 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
OverviewThe conceptual CareLight sensor technology has already demonstrated its better performance of physiological monitoring (http://atlasofscience.org/tag/carelight) with multiplexed functionalities over available smart devices to fulfil a fast growing demand of mobile healthcare and personal health monitoring at rest and during physical activity. The project will utilise LU patented sensor technology (GB patent: 2524919) to create a continuous human vital signs monitoring prototype with a heterogonous engineering architecture and it's use for physiological monitoring as requested by clinicians, individuals and even sportsmen/women, will be validated through gold standard testing procedures. The new generation of power-saving opto-electronic patch sensor (POPS) prototype created in this project will provide reliable signals that are motion resistant and not prone to failure with existing smart devices for a period (>24 hours) of real-time human vital signs monitoring. The POPS when combined with an ergonomic design and a power-saving engineering architecture will be fully compliance with clinical regulated monitoring devices and data management systems, and will be perfectly suited to medical and sporting monitoring environments.Excellence in Science and TechnologyThe POPS will be one of the outcomes derived from solid fundamental research of opto-physiological interaction (NASA/TM-2011-216145) against existing lambert-Beer law based and motion artefact photoplethysmography (PPG). LU opto-physiological modelling based physiological monitoring work was recognised as being at the forefront of worldwide pulse oximetry research by Drexel University in 2008 (www.pages.drexel.edu/~kmg462/currentresearch.html). Together with power-saving architecture (http://pubs.rsc.org/en/content/articlelanding/2013/CP/C3CP52036F#!divAbstract), fundamental research will be undertaken to provide optimal solutions toward viable innovative products, The sensor will be integrated into wearable products with power sources, flexible electronics, materials and manufacturing processes explored in a user-centred design context. The POPS will possess miniaturised, system integrated and ultra-light weight features with a reliable and better performance to deliver one-stop solutions in critical signs monitoring. The developed POPS prototype will be tested using standardised physiological testing procedures in order to demonstrate its reliability and resistance to motion artefact. The POPS prototype offers both clinicians and scientists the ability to gain more in-depth knowledge of physiological processes within the body as its design makes it easy to collect data continuously over long periods of time as it is ultra-light weight, comfortable, unobtrusive and does not impede or restrict movement.ObjectivesThe project will consolidate the enabling optoelectronic sensing tech into power-saving architecture design of user prototype leading to healthcare and sport physiological monitoring application. The objectives of the project will be created with its unique characteristics of forthcoming POPS as follows:1) Motion resistance physiological monitoring with a sound fundamental of opto-physiological interaction. 2) Heterogeneous design to provide enhanced functionalities of POPS and a better performance during the measurements inside and outdoor.3) Physiological testing will be undertaken not only to validate heterogonous design in power consumption but also to gain further insight into physiological processes within the body both at rest and during intensive physical activity through continuous, long duration, minimally intrusive measurement.4) Multidisciplinary research across photonics, design, healthcare and sport monitoring application to lead a new research paradigm of site/field sport physiologic monitoring even assessment in a real-time.
概述概念上的CareLight传感器技术已经证明了其更好的生理监测性能(http://atlasofscience.org/tag/carelight)),与现有的智能设备相比具有多种功能,以满足快速增长的移动医疗和个人健康监测的需求。该项目将利用LU专利传感器技术(GB专利:2524919)创建具有异种工程架构的连续人体生命体征监测原型,并根据临床医生、个人甚至运动员/女性的要求将其用于生理监测,将通过黄金标准测试程序进行验证。该项目创建的新一代节能型光电贴片传感器(POPS)原型将提供可靠的信号,这些信号不会移动,并且在现有智能设备上不容易出现故障,用于一段时间(>;24小时)的实时人体生命体征监测。POPS与人体工学设计和节电工程架构相结合,将完全符合临床规范的监测设备和数据管理系统,并将完全适合医疗和体育监测环境。卓越的科学技术POPS将是针对现有的基于朗伯-比尔定律和运动伪影的光生理相互作用的坚实基础研究(美国宇航局/TM-2011-216145)的成果之一。基于LU光生理模型的生理监测工作被德雷克塞尔大学在2008年(www.pages.drexel.edu/~kmg462/currentresearch.html).认定为世界脉搏血氧仪研究的前沿将与节能架构(http://pubs.rsc.org/en/content/articlelanding/2013/CP/C3CP52036F#!divAbstract),一起进行基础研究,为可行的创新产品提供最佳解决方案,传感器将集成到可穿戴产品中,在以用户为中心的设计背景下探索电源、灵活的电子产品、材料和制造工艺。POPS将拥有小型化、系统集成和超轻重量的功能,具有可靠和更好的性能,为关键标志监测提供一站式解决方案。开发的POPS原型将使用标准化的生理测试程序进行测试,以证明其可靠性和对运动伪影的抵抗力。POPS原型为临床医生和科学家提供了更深入了解人体内生理过程的能力,因为它的设计使得长期连续收集数据变得容易,因为它超轻、舒适、不显眼,不会阻碍或限制移动。目标该项目将使能光电传感技术整合到用户原型的节电架构设计中,从而导致医疗保健和运动生理监测应用。该项目的目标将根据即将推出的持久性有机污染物的独特特点如下:1)具有良好的光-生理相互作用基础的运动阻力生理监测。2)异质设计,为POP提供增强的功能,并在室内和室外测量时获得更好的性能。3)生理测试将不仅验证电力消耗的异质设计,还将通过连续、长时间、最小侵入性的测量进一步了解人体内的生理过程。4)跨光子学、设计、医疗保健和运动监测应用的多学科研究,引领场地/场地运动生理监测甚至实时评估的新研究范式。
项目成果
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其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
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LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
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2021 - 期刊:
- 影响因子:0
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吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
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