权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

MINORITY PREDOCTORAL FELLOWSHIP PROGRAM

少数族裔博士前奖学金计划

基本信息

批准号：
6401186
负责人：
MARIA G VALDOVINOS
金额：
$ 1.05万
依托单位：
UNIVERSITY OF KANSAS LAWRENCE
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
起止时间：
2001-08-05 至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/6401186
关键词：
antipsychotic agents clinical research developmental psychology drug adverse effect human subject human therapy evaluation mental retardation minority health professional minority institution research support neuropharmacology neuropsychology neurotoxicology patient monitoring device psychopharmacology technology /technique development

项目摘要

The specific aim of this study is to attempt to develop an efficient system for monitoring adverse side effects of psychotropic medication on people with developmental disabilities and to evaluate if use of this system results in more reliable reports than what is currently reported of adverse side effects by direct-care staff and possible changes in the prescription of medication by a psychiatrist or prescribing physician. Participants will include adults with the formal diagnosis of mental retardation and are currently receiving psychotropic medication and are living in group home settings in the community requiring supervision 24 hours a day. An evaluation across different group home settings will occur simultaneously in a multiple baseline design (effects are demonstrated by introducing the intervention to different baselines at different time ). Computers provided in each home will have a program that provides the intervention to be used weekly. The program will be designed to present "Yes" and "No" questions and rating scales to direct-care staff about potential side effects as well as target behaviors such as aggression, self-injurious behavior, and property destruction. Data will be summarized as number, class and severity of adverse side effects reported weekly and changes in medication type, dose, and number.

本研究的具体目的是试图开发一种有效的系统，用于监测精神药物对发育障碍患者的不良副作用，并评估使用该系统是否会产生比目前报告的直接护理人员的不良副作用更可靠的报告，以及精神科医生或处方医生处方药物的可能变化。参加者将包括被正式诊断为智力迟钝的成年人，目前正在接受精神药物治疗，并住在社区的集体之家，需要每天24小时的监督。在多基线设计中，将同时对不同团体之家环境进行评价（通过在不同时间将干预措施引入不同基线来证明效果）。每个家庭提供的计算机将有一个程序，提供每周使用的干预。该计划旨在向直接护理人员提供“是”和“否”问题和评级量表，以了解潜在的副作用以及攻击、自伤行为和财产破坏等目标行为。数据将总结为每周报告的不良副作用的数量、类别和严重程度以及药物类型、剂量和数量的变化。