DEPRESSION IN ADAPTATION TO OPEN-HEART SURGERY

申请人？的描述：拟议的研究将审查的影响， 抑郁症患者的身心适应 开胸手术越来越多的证据表明，抑郁症可能 影响冠心病的发生和发展， 心脏事件后恢复。虽然一些生理和行为 已经提出了解释这些关联的途径， 心理机制很少被考虑。除了评估 抑郁症对心脏手术适应的影响，本研究将探讨 社会认知变量作为这些影响的中介的作用。的 本研究的具体目的是检验以下假设：（1）低 术前抑郁水平将预测较短的住院时间 （2）术前抑郁水平较低将预示 术后6个月心绞痛减少，身体功能改善;（3）降低 术前抑郁水平将预示着术后6个月的焦虑减少。 手术;和（4）这些影响将部分介导的结果 对行为和社会方面的期望和效能期望 与恢复相关的活动。该项目旨在推进理论 了解心理社会因素与身体因素之间的关系 病这项研究的其他长期目标包括改善 术前识别心脏病患者的不良结局风险， 为这一人群制定心理社会干预措施，最终， 提高手术效果和长期适应慢性 疾病

Applicant?s Description: The proposed study will examine the effects of depressive symptomatology on physical and psychological adaptation to open-heart surgery. There is growing evidence suggesting that depression may influence the development and progression of coronary heart disease as well as recovery following cardiac events. While several physiological and behavioral pathways have been proposed to explain these associations, potential psychological mechanisms have rarely been considered. In addition to evaluating effects of depression on adaptation to cardiac surgery, this study will examine the role of social cognitive variables as mediators of these effects. The specific aims of this study are to test the following hypotheses: (1) Lower levels of preoperative depression will predict shorter hospitalizations following surgery; (2) Lower levels of preoperative depression will predict less angina and better physical functioning six months after surgery; (3) Lower levels of preoperative depression will predict less anxiety six months after surgery; and (4) These effects will be partially mediated by outcome expectancies and efficacy expectancies regarding behavioral and social activities associated with recovery. This project seeks to advance theoretical understanding of the relationship between psychosocial factors and physical illness. Additional long-term goals of this research include improving pre-surgical identification of cardiac patients at risk for poor outcomes, the development of psychosocial interventions for this population, and ultimately, the enhancement of surgical outcomes and long-term adaptation to chronic disease.