DEVELOPMENTAL BIOLOGY TRAINING PROGRAM

描述(申请人提供)：发育生物学领域在最近几年已经成熟，主要是通过整合许多生物科学，包括遗传学、细胞生物学、胚胎学、生理学、分子生物学、生物化学和进化生物学。对发育的了解很可能是许多医学的基础，并最终可能为许多问题提供重要信息，从先天性缺陷到衰老。明尼苏达大学的发育生物学专业由DBC提供，DBC的总部设在遗传学、细胞生物学和发育系(DGCB&D)，这是医学院和生物科学学院内的一个全大学系。然而，DBC接纳了来自大学内其他系的成员，如神经科学和植物生物学。DBC每年组织一次广受欢迎的明尼苏达大学发育生物学研讨会，举办一系列关于发育生物学的晚间研究研讨会，让研究生和博士后研究人员介绍他们的工作，并促进明尼苏达大学发育生物学家之间的互动和合作。培训员都是该中心的成员，使用许多不同的模式生物在发育生物学的不同领域开展工作，包括老鼠、鸡、斑马鱼、非洲爪哇、果蝇、线虫、网纹盘藻、拟南芥以及人类。发育生物学实习生的主要研究生课程是分子、细胞、发育生物学和遗传学(MCDB&G)研究生课程。该课程围绕实验室技术、分子生物学、遗传学、细胞生物学、发育生物学、文献分析和不同系统中的实验室轮换等强大的核心研究生课程而建立。培训师有强大的研究计划，以及致力于研究生和博士后培训的良好记录。8名博士前实习生将被选为培训补助金，主要来自MCDB&G的研究生，但也可能来自其他研究生项目，如神经科学和生物化学、分子生物学和生物物理学。受训者在培训者的实验室开始论文工作后，将得到一到三年的支持。培训实验室和核心设施都配备齐全。

DESCRIPTION (Provided by Applicant): The field of developmental biology has matured in recent years, largely through the integration of much of the biological sciences, including genetics, cell biology, embryology, physiology, molecular biology, biochemistry, and evolutionary biology. An understanding of development may well be fundamental to much of medicine and may ultimately contribute important information to many problems, ranging from congenital defects to senescence. The focus for developmental biology at the University of Minnesota is provided by the DBC, which is based in the Department of Genetics, Cell Biology, and Development (DGCB&D), an all-university department within both the School of Medicine and the College of Biological Sciences. However, the DBC embraces members from other departments within the University such as Neuroscience and Plant Biology. The DBC organizes a popular annual University of Minnesota Developmental Biology Symposium, runs a series of evening research seminars in developmental biology where graduate students and postdoctoral researchers present their work, and promotes interactions and collaborations among developmental biologists at the University of Minnesota. The trainers are all members of the Center and work in diverse areas of developmental biology using many different model organisms, including mice, chickens, zebrafish, Xenopus, Drosophila, C. elegans, Dictyostelium, and Arabidopsis, as well as humans. The principal graduate program for developmental biology trainees is the Molecular, Cellular, Developmental Biology, and Genetics (MCDB&G) graduate program. This program is built around strong core graduate courses in laboratory techniques, molecular biology, genetics, cell biology, developmental biology, literature analysis, and laboratory rotations in diverse systems. The trainers have strong research programs and strong records of commitment to graduate and postdoctoral training. Eight predoctoral trainees will be chosen for training grant support, largely from the pool of graduate students in MCDB&G, but possibly also from other graduate programs, such as neuroscience and biochemistry, molecular biology and biophysics. Trainees will be supported for one to three years, after they have begun their thesis work in the laboratories of the trainers. The training laboratories and core facilities are all well equipped.