Training Program in Developmental and Stem Cell Biology

 描述(申请人提供)：发育和干细胞生物学培训计划的目标是为来自不同背景的博士前个人提供科学和学术培训，以追求研究生涯，并成为生物医学科学的未来领导者。该培训计划是威尔·康奈尔医学研究生院计划的一个组成部分，但又是一个独立的部分，该计划由威尔·康奈尔医学院和斯隆-凯特琳研究所联合管理。该项目是跨学科的，包括其九个研究项目中六个的发育和干细胞生物学研究项目，包括细胞和发育生物学、生物化学和结构生物学、分子生物学、神经科学、药理学和生理学、生物物理学和系统生物学。该培训计划包括来自两个机构的46名教职员工，他们在学术研究和博士后和博士后培训方面拥有丰富的集体经验。培训计划的研究兴趣体现在以下五个领域：发育遗传学、组织和器官的模式、干细胞、发育中的信号传递以及人类发育和疾病。符合条件的学生由项目主任、副主任和执行委员会根据他们对卓越的承诺来挑选。该培训计划包括一年级的核心课程和三次实验室轮换，二年级的两门标志性课程--“发育生物学原理”和“干细胞”，以及二年级准备ACE(候选资格考试)的辅导助学金写作课程，以及组织生物学和发育方面的以期刊文章为基础的焦点小组，以及在二至五年级参加研究生研究研讨会。符合条件的受训者将在三到四年的培训中被挑选出来，获得津贴和学费支持。受训者由项目主任指导，他们参加专门的培训项目活动，包括特邀演讲者研讨会、正在进行的研究研讨会、发育生物学和干细胞生物学研讨会和研讨会。自4年前第一个资助期开始以来，已经选出了11名博士前学员，其中4名是代表性不足的少数民族。第一批学生在过去一年毕业；他们目前是博士后研究员或NIH研究员。我们已经能够评选出优秀的学生，如总共28份出版物，其中14份是第一作者手稿，53份海报和21份学生口头报告。在过去的十年里，参与发育和干细胞生物学培训计划的教职员工和学生人数稳步增加。目前，它包括46名教师导师和134名(2009年为54名学生)培训符合资助条件的学生，其中20名(15%)是少数民族学生(2009年为7名学生；13%)。为了继续为致力于卓越的学生提供培训，我们寻求支持总共六名研究生在他们的第三和第四年的培训。

 DESCRIPTION (provided by applicant): The objective of the Developmental and Stem Cell Biology Training Program, for which this application is seeking continued support, is to provide scientific and academic training to pre-doctoral individuals from diverse backgrounds to pursue investigative careers and become future leaders in the biomedical sciences. The Training program is an integral but distinct part of the umbrella Weill Cornell Graduate School of Medical Sciences Program, which is jointly administered by the Weill Cornell Medical College and the Sloan-Kettering Institute. The program is inter-disciplinary and incorporates research programs in Developmental and Stem Cell Biology from six out of its nine Programs of Study, including Cell and Developmental Biology, Biochemistry & Structural Biology, Molecular Biology, Neurosciences, Pharmacology, and Physiology, Biophysics, & Systems Biology. The Training Program includes 46 faculty members from both institutions with strong collective experience in academic research and training of pre- and post-doctoral students. The research interests in the Training Program are represented by the following five areas: Developmental Genetics, Patterning of Tissues and Organs, Stems Cells, Signaling in Development, and Human Development and Disease. Eligible students are selected by the Program Director, the co-Director and the Executive Committee, based on their promise of excellence. The Training program includes a core curriculum of courses and three laboratory rotations in year-1, two signature courses, "Principles of Developmental Biology" and "Stem Cells", and a tutored grant writing course in preparation for the ACE (Admission to Candidacy Exam) during year-2, and journal article-based Focus Groups in Tissue Biology and Development, and participation in Graduate Student Research Seminars during years 2 to 5. Eligible trainees are selected for stipend and tuition support during years 3 and 4 of training. Trainees are mentored by the Program Director, and they attend specialized Training Program events, including seminars by invited speakers, Research-in-Progress seminars, and Developmental Biology and Stem Cell Biology workshops and symposia. Since the start of the first funding period 4 years ago, 11 pre-doctoral trainees have been selected, 4 of who are underrepresented minorities. The first group of students graduated during the past year; they are presently post-doctoral fellows or NIH fellows. We have been able to select outstanding students, as illustrated by a total 28 publications, 14 of which are first-author manuscripts, and 53 posters and 21 oral presentations given by the students. The number of faculty and students engaged in the Developmental and Stem Cell Biology Training Program has steadily increased over the past decade. Presently, it includes 46 faculty mentors and 134 (up from 54 students in 2009) training grant- eligible students, 20 of who (15%) are minority students (up from 7 students in 2009; 13%). To continue with providing training of students with a commitment to excellence, we seek support for a total of six graduate students in their third and fourth year of training.