GENERIC DATABASE FOLLOW UP STUDY

通用数据库后续研究

• 批准号: 6441964
• 负责人: ANN STARK
• 金额: $ 2.88万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6441964
• 关键词: child physical development; clinical research; developmental neurobiology; disease /disorder proneness /risk; family structure /dynamics; human morbidity; human subject; information systems; longitudinal human study; low birth weight infant human; outcomes research; preschool child (1-5); social support network; socioeconomics; stress

This multicenter study is performed to assess outcome in a large cohort of extremely low birth weight (ELBW) infants. One of the primary aims is to track and successfully follow at 18 months of age, more than 80% of babies entered into the Generic Data Base of the Neonatal Research Network with birth weights 401-1000grams. Of special importance is monitoring changes over time associated with changes in care practices and survival. In addition, it is important to assess outcome in infants who have participated in randomized clinical trials performed by the Neonatal Research Network. The results of this study will provide current information on growth, neurodevelopment, and the prevalence of specific morbidities in this population. Additionally, the effects of family socioeconomic status and family stress, as well as the utilization of support services will be characterized.

这项多中心研究是为了评估一个大型极低出生体重（ELBW）婴儿队列的结局。主要目标之一是跟踪和成功地跟踪18个月大的婴儿，超过80%的婴儿进入新生儿研究网络的通用数据库，出生体重为401- 1000克。特别重要的是监测随着时间的推移与护理实践和生存的变化有关的变化。此外，重要的是要评估参与新生儿研究网络进行的随机临床试验的婴儿的结局。本研究的结果将提供关于该人群的生长、神经发育和特定发病率的最新信息。此外，家庭社会经济地位和家庭压力的影响，以及利用支持服务的特点。