Sustainable life support for Martian and lunar exploration: genetic engineering and extra-terrestrial cultivation of edible cyanobacterium

火星和月球探索的可持续生命支持：基因工程和可食用蓝细菌的外星培养

• 批准号: 1902653
• 金额: --
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1902653
• 关键词: Sustainable; life; support; Martian; lunar

A mission to Mars and the establishment of a base on the moon are envisaged in the next few decades. However, supplying all consumables, such as food, from Earth is impractical and prohibitively expensive. A major challenge is therefore the development of sustainable technologies for food production on spacecraft and within bases. The edible cyanobacterium Arthrospira platensis has been proposed as one such foodstuff given its rapid growth, nutritional value and efficiency of CO2 conversion into biomass. This project will explore the potential of A. platensis and focus on: i) metabolic engineering to add essential nutrients and improve palatability; ii) design of a photobioreactor for efficient cultivation; iii) modelling of growth performance under mission conditions.

设想在今后几十年内进行一次火星使命并在月球上建立一个基地。然而，从地球上提供所有的消耗品，如食物，是不切实际的，而且价格昂贵。因此，一项重大挑战是开发在航天器上和基地内进行粮食生产的可持续技术。鉴于其快速生长、营养价值和将CO2转化为生物质的效率，可食用蓝藻Arthrospira platensis已被提议作为这样的食品之一。本项目将探索A. platensis和重点：i）代谢工程，以添加必需营养素并改善适口性; ii）设计用于高效培养的光生物反应器; iii）在使命条件下的生长性能建模。

项目成果

Over-expression of a cyanobacterial gene for 1-deoxy-d-xylulose-5-phosphate synthase in the chloroplast of Chlamydomonas reinhardtii perturbs chlorophyll: carotenoid ratios.

• DOI: 10.1016/j.jksus.2022.102141
• 发表时间: 2022-08
• 期刊: JOURNAL OF KING SAUD UNIVERSITY SCIENCE
• 影响因子: 3.8
• 作者: Al Hoqani, Umaima;Leon, Rosa;Purton, Saul
• 通讯作者: Purton, Saul