A COBRE CENTER FOR CARDIOVASCULAR RESEARCH

描述（由申请人提供）：本COBRE的总体目标 倡议是在纽约建立一个心血管研究中心， 夏威夷大学。 这项建议是建立在几个令人兴奋的新发展， 在过去的四年里，大学使这一倡议成为可能。 心血管系统的生物学，特别是病理学， 是一个新兴的研究主题在呃。NIH资助的主要研究者 指导这些研究工作已经建立了跟踪记录， 合作和有效的指导计划，为有前途的年轻教师。 有了这个中心提案的资金，这些国家认可的 研究人员，具有分子和细胞生物学，生物化学和 遗传学，将有机会，在校长的指导下， 调查员，以扩大和加强他们目前的研究和指导 能力的这些目标将通过三个主要具体措施来实现。 目的： 1.建立一个由资深调查员组成的强大的指导小组， 具有血管和 心血管生物学，以支持职业发展的一组选定的 有前途的年轻调查员 2.通过发展 实验室核心设施、行政支持和资源，以便 提高既有研究人员的研究竞争力， 年轻的教师 3.制定一项战略计划，以协助征聘和 留住有才华和资金的年轻教师和既定的研究人员 在UH的教师职位，以促进一个持续的增长 心血管研究计划成为UH的主要研究学科， 稳定的供资机会，不仅平行，而且最终取代 COBRE资金。

DESCRIPTION (provided by applicant): The overall goal of this COBRE initiative is to develop a Center for Cardiovascular Research at the University of Hawaii (UH). This proposal is built upon several exciting new developments at the University over the last four years that have made this initiative possible. The biology and particularly the pathobiology of the cardiovascular system has been an emerging research theme at UH. The NIH-funded principal investigators directing these research efforts have established a track record of collaboration and an effective mentoring program for promising young faculty. With funds from this center proposal, these nationally recognized investigators, with expertise in molecular and cell biology, biochemistry and genetics, would have the opportunity, under the direction of the Principal Investigator, to expand upon and enhance their current research and mentoring capabilities. These goals would be achieved through three primary specific aims: 1. The development of a strong mentoring group of established investigators, with interdisciplinary but complementary backgrounds in vascular and cardiovascular biology, to support the career growth of a selected group of promising young investigators. 2. The enhancement of infrastructure support through the development of laboratory core facilities, adminstrative support and resources, in order to increase the research competitiveness of both established investigators and young faculty. 3. The development of a strategic plan to assist in the recruitment and retention of talented and funded young faculty and established investigators in faculty positions at UH in order to promote the continued growth of a cardiovascular research program into a major research discipline at UH with stable funding opportunities to not only parallel but to eventually replace COBRE funding.