Antimicrobial activity and formulation of propolis extracts

蜂胶提取物的抗菌活性及配方

• 批准号: 1915080
• 金额: --
• 依托单位: University of Birmingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1915080
• 关键词: Antimicrobial; activity; formulation; propolis; extracts

Bees are sociable insects that leave and work in the hive. In order to be protected from outside enemies such as bacteria, fungi and other microorganisms they seal the hive with propolis that the bees have to produce themselves. Propolis has all the antimicrobial and antibacterial properties required in addition to its resinous character to be used as a sealing material. In addition, propolis serves as an antioxidant agent due to its reducing character properties that are utilised by the bee hive. At first this project will investigate the composition of propolis in order to understand its anti-microorganism character. At a second stage methods will be developed in order to extract the active ingredients paying particular attention in the retention of their biological activity. At a final stage, complex formulation designs and formulation routes for the fabrication of different types of particles will be investigated, in order to produce formulations which are tailored to deliver propolis and synergistic active agents with optimised activity in the food, cosmetics and pharmaceutical applications.

蜜蜂是群居昆虫，离开蜂巢在蜂巢里工作。为了保护蜜蜂免受细菌、真菌和其他微生物等外部敌人的侵害，它们用蜜蜂必须自己生产的粪便密封蜂巢。蜂胶具有所有的抗菌和抗细菌特性，除了它的抗菌特性，被用作密封材料。此外，由于其被蜂巢利用的还原特性，蜂胶可用作抗氧化剂。本计画首先将探讨其组成，以了解其抗微生物特性。在第二阶段，将开发提取活性成分的方法，特别注意保留其生物活性。在最后阶段，将研究用于制造不同类型颗粒的复杂配方设计和配方路线，以生产定制的配方，以在食品，化妆品和药物应用中提供具有优化活性的协同活性剂。