Core--Injury and functional assessment

描述：(使用摘要)：该核心将为PPG中提出的活体实验提供技术支持。Core将使用纽约大学的冲击器应用大鼠和小鼠的脊髓损伤(SCI)模型，以协助进行项目3和4中提出的体内研究。Core C的主要目标是为动物研究建立和维护啮齿动物脊髓损伤模型；实施和执行PPG研究人员提出的体内实验方案；以及评估PPG研究人员实施干预后功能结果的变化。这个核心的总体目标是支持PPG研究人员进行活体实验，并确定ES细胞移植在改善脊髓损伤后功能恢复方面的有效性。

DESCRIPTION: (Abstract used): This Core will provide technical support for in vivo experiments proposed in the PPG. The Core will apply rat and mouse models of spinal cord injury (SCI) using an NYU Impactor to assist in the conduction of in vivo studies proposed in Projects 3 and 4. The majors goals of Core C are to establish and maintain rodent SCI models for animals studies; to implement and execute in vivo experimental protocol proposed by PPG investigators; and to assess changes in functional outcomes following interventions administered by PPG investigators. The overall objective of this Core is to support PPG investigators in conducting in vivo experiments and in determining the efficacy of ES cell transplantation for improving functional recovery after SCI.