CORE--NUCLEIC ACID SYNTHESIS FACILITY

核心——核酸合成设施

• 批准号: 6477409
• 负责人: PONZY LU
• 金额: $ 16.54万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6477409
• 关键词: antisense nucleic acid; biomedical facility; nucleic acid chemical synthesis

The facility intends to synthesize 2 grams of oligomer per year for the Program. The oligomer including 1 gram S-DNA, 700 mg normal DNA and 300 mg RNA and special modified oligos. With the installation of the second Expedite Synthesizer we should be able to offer oligonucleotides at costs that will remain stable in the next 4-5 years. The facility's Technical Director, Dr. Xiaolin Zhang, is responsible for quality control of the DNA produced daily.

该设施计划每年合成2克低聚物， 程序. 所述寡聚体包括1克S-DNA、700 mg正常DNA和 300毫克RNA和特殊修饰的寡核苷酸。 可以安装 第二个快速合成器，我们应该能够提供寡核苷酸 成本在未来4-5年内将保持稳定。 该设施的 技术总监张晓林博士负责质量 控制每天产生的DNA