CORE--RADIATION FACILITY
核心--辐射设施
基本信息
- 批准号:6443864
- 负责人:
- 金额:$ 34.88万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2001
- 资助国家:美国
- 起止时间:2001-04-02 至 2002-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The Radiation Core will provide the irradiation in support of all
of the projects in the program. This core is housed in the Lombardi
Cancer Center and currently consists of a J.L Shepard Mark I, Model
30, Cesium Irradiator. This Mark I is specifically designed for
experimental gamma-irradiations. It contains a 2,200 Ci 137 Cs
source. Tissue culture flasks are irradiated by stacking them on
the rotating platform. A special rotating tube holder can
accommodate test tubes with volumes up to 50 ml. A pie-shaped
rotating mouse holder allows simultaneous whole-body irradiations
of a dozen mice at a time. The cesium irradiator is suitable for the
majority of the irradiations required by this program; however, the
inability to effectively focus and block the beam makes it difficult
to use the instrument for partial body irradiations, such as tumor
irradiations in the flanks of mice. Also, the penetrability of the
radiation cannot be controlled because the photon energy cannot be
modulated. For these reasons, we are requesting the purchase of a
low cost, portable, x-ray machine, that cannot be dedicated to the
experimental work of the program. The requested x-ray machine is the
RS2000, manufactured by Rad-Source, a division of Microfocus
Imaging, Inc of Wheeling, IL. Dr. Timothy Jorgenson is Director of
the Radiation Core. His responsibilities include training personnel
in the proper and safe use of the instruments, and ensuring
compliance with NRC regulations. Dr. Jorgenson chairs an Internal
Advisory Committee. The Committee meets as needed to set rules and
policies from instrument use, and to make decisions concerning
maintenance and repairs. The committee guarantees fair and equitable
use of the instruments among the investigators.
辐射核心将提供辐射,以支持所有
该计划中的项目。这个核心被安置在隆巴迪
癌症中心,目前由J.L.Shepard Mark I,Model
30,铯辐照器。这款Mark I是专门为
实验性的伽马辐射。它含有2200Ci 137Cs
消息来源。将组织培养瓶堆叠在一起进行照射
旋转平台。一种特殊的旋转管座可以
容纳容量不超过50毫升的试管。一个馅饼形的
旋转鼠标支架可同时进行全身照射
一次杀死十几只老鼠。这种铯辐照器适用于
该计划所需的大部分照射;然而,
无法有效地聚焦和阻挡光束使其难以实现
使用该仪器进行全身局部照射,如肿瘤
照射小鼠的侧翼。此外,可穿透性
辐射不能被控制,因为光子能量不能
调制过的。出于这些原因,我们请求购买
低成本、便携的X光机,不能专用于
该方案的试验性工作。所要求的X光机是
RS2000,由MicroFocus的一个部门Rad-Source制造
伊利诺伊州惠灵市的成像公司。蒂莫西·乔根森博士是
辐射核心。他的职责包括培训人员
正确和安全地使用仪器,并确保
遵守NRC的规定。约根森博士主持了一项内科
咨询委员会。委员会视需要开会,以制定规则和
工具使用的政策,并就以下问题做出决定
维护和维修。该委员会保证公平和公平
调查人员对仪器的使用情况。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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TIMOTHY J JORGENSEN其他文献
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{{ truncateString('TIMOTHY J JORGENSEN', 18)}}的其他基金
DNA REPAIR GENE POLYMORPHISMS AND BREAST CANCER RISK
DNA 修复基因多态性与乳腺癌风险
- 批准号:
6648137 - 财政年份:2003
- 资助金额:
$ 34.88万 - 项目类别:
HORMONAL MODIFICATIONS OF RADIATION INDUCED MUTAGENESIS
辐射诱变的荷尔蒙改变
- 批准号:
2114514 - 财政年份:1995
- 资助金额:
$ 34.88万 - 项目类别:
HORMONAL MODIFICATIONS OF RADIATION INDUCED MUTAGENESIS
辐射诱变的荷尔蒙改变
- 批准号:
2009728 - 财政年份:1995
- 资助金额:
$ 34.88万 - 项目类别: