CATALYTIC ANTIBODY & HAPTEN COMPLEX & MURINE CYTOSOLIC EPOXIDE HYDROLASE STRUCT

催化抗体

• 批准号: 6491100
• 负责人: DAVID W CHRISTIANSON
• 金额: $ 14.27万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2002-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6491100
• 关键词: bioimaging /biomedical imaging; biological products; biomedical resource; proteins; radiography; structural biology

X-ray diffraction feasibility studies conducted on crystals of the alkaline phosphatase-vanadate complex resulted in a complete data set to a resolution of 3.2
. The crystals belong to space group P6322 with the unit cell dimensions of a=b=162.7 and c=141.4
, and a dimer per asymmetric unit. The structure was determined by molecular replacement methods. The enzyme active site reveals a presence of metal and vanadate ions.

X射线衍射可行性研究进行的晶体的 碱性磷酸酶-钒酸盐复合物产生完整的数据集 分辨率为3.2
. 晶体属于空间群P6322 其中晶胞尺寸为a=B=162.7和c=141.4
和二聚体 每个不对称单元。 通过分子结构测定， 替换方法。 酶活性位点揭示了 金属和钒酸盐离子。