360 Degree Sinuscope with Integrated Forward View

具有集成前视功能的 360 度鼻窦镜

• 批准号: 6484929
• 负责人: Michelle D Simkulet
• 金额: $ 37.5万
• 依托单位: INTERSCIENCE, INC.
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-01 至 2004-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6484929
• 关键词: biomedical equipment development; clinical research; computer program /software; computer system design /evaluation; diagnosis design /evaluation; endoscopy; human subject; image enhancement; image processing; otorhinolaryngologic surgery; paranasal sinus; patient oriented research; sinusitis

All endoscopic applications would benefit from a significant increase in available field of view though major modification to the endoscope. Under the Phase I effort, InterScience Inc. has successfully demonstrated the application of its patented 360-degree/forward view imaging technology to small diameter digit endoscopes, with specific application to sinus surgery. In Phase II, we will significantly advance the development of this technology to the point of assembling fully integrated prototype 360 degree/forward view endoscopic systems and conducting initial clinical evaluation of the devices. The proposed Phase II effort will comprise optical design, development and assembly of a custom rigid endoscope system with an integrated 360 degree and forward view and real time image processing. Initial efforts include laboratory optical testing and cadaver testing for system optimization, and finally clinical evaluation in sinus surgery and airway evaluation applications. A successful Phase II effort will provide the necessary foundation to transfer the technology to additional endoscopic applications and to develop appropriate licensing arrangements with existing medical endoscope manufacturers. At this time, we have received an expression of interest from Karl Storz GmbH & Co., a worldwide leader in endoscope production, in the development and commercialization of this technology. PROPOSED COMMERCIAL APPLICATIONS: NOT AVAILABLE

通过对内窥镜进行重大修改，所有内窥镜应用都将受益于可用视野的显著增加。在第一阶段的努力下，InterScience Inc.成功展示了其专利360度/前视成像技术在小直径内窥镜上的应用，特别是在鼻窦手术中的应用。在第二阶段，我们将大大推进这项技术的发展，组装完全集成的原型360度/前视内窥镜系统，并对这些设备进行初步临床评价。拟议的第二阶段工作将包括光学设计、开发和组装定制的刚性内窥镜系统，该系统具有集成的360度和前向视图以及真实的时间图像处理。最初的工作包括实验室光学测试和尸体测试系统优化，最后在鼻窦手术和气道评估应用的临床评价。第二阶段的成功将为将技术转移到其他内窥镜应用领域以及与现有医疗内窥镜制造商制定适当的许可安排提供必要的基础。 目前，我们已收到Karl Storz GmbH & Co.的意向书，在内窥镜生产、该技术的开发和商业化方面处于世界领先地位。拟议的商业应用：不可用