C-View Semi-rigid Endoscope for Urological Applications

适用于泌尿外科应用的 C-View 半刚性内窥镜

• 批准号: 7556578
• 负责人: Michelle D Simkulet
• 金额: $ 35.18万
• 依托单位: INTERSCIENCE, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-02-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7556578
• 关键词: Advanced Development; Animal Welfare; Appendix; Arts; Bibliography; Biopsy; Bladder; Cadaver; Caliber; Country; Development; Disease; Distal; Electrocoagulation; Endoscopes; Ensure; Environment; Environmental Impact; Equipment; Evaluation; Excision; Foundations; Future; Government; Hand; IACUC; Image; Imagery; Imaging technology; Injection of therapeutic agent; International; Intubation; Invasive; Laparoscopy; Left; Length; Lesion; Lighting; Location; Malignant neoplasm of urinary bladder; Medical Surveillance; Modeling; Names; Nature; Numbers; Operative Surgical Procedures; Optics; Other Resources; Patients; Persons; Phase; Positioning Attribute; Principal Investigator; Prior Therapy; Procedures; Process; Purpose; Research; Research Ethics Committees; Retrograde pyelogram; Scheme; Software Design; Source; System; Technology; Testing; Time; Trauma; Urethra; Urology; Vertebrates; Work; abstracting; base; commercialization; concept; design; expiration; human subject; improved; innovative technologies; optical sensor; programs; prototype; research and development; sensor; urologic

DESCRIPTION (provided by applicant): Project Summary/Abstract The proposed fast track effort is aimed at integrating InterScience's C-View imaging technology, capable of providing an uninhibited 240 degree vertical and 360 degree panoramic field of view to a single image plane, with distal sensor technology, an innovative illumination scheme and semi-rigid endoscope packaging. The C-View semi- rigid scope is broadly applicable to urological procedures, laparoscopy and endoscopic general surgery. In urology specifically, this technology will not only enhance the visualization of the entire bladder and urethra, but will also aid most urologic endoscopic procedures such as bladder biopsies and fulguration, intubation of ureteral orifaces for retrograde pyelograms or passage of wires, intra-vesical injections and trans-urethral resections. Using this innovative technology, inspecting the bladder, photographing bladder lesions and other disease processes will aid in future surveillance with more a precise location of prior therapy. The all viewing, single field of view minimizes procedure time and discomfort to the patient by eliminating intra-procedural swapping of various angled scopes and/or manipulation of the flexible scope tip, all while ensuring procedure thoroughness. The overall design of the proposed scope is a tremendous advance in endoscope technology, taking advantage of state of the art in optical design, optical component manufacturing, imaging sensors and illumination technology. This application is being pursued through fast-track based on the highly commercial nature of the technology and the impact on minimally invasive surgery applications. In an effort to streamline the research and development process of the C-View semi-rigid endoscope, the Phase I effort is designed to provide a design, testing, and benchtop demonstration foundation for the continued development effort of Phase II and the commercialization beyond. The overall objective of the proposed Phase II effort is to advance the development of the C-View endoscope through the integration and assembly of working prototypes and cadaver model testing, based on the foundation established in Phase I. Project Narrative The C-View semi-rigid scope is specifically applicable to bladder cancer surveillance, but also will provide benefits more broadly to urological procedures, laparoscopy and endoscopic general surgery. The unprecedented ultra-wide field of view of this C-View semi-rigid endoscope would greatly improve image consistency, and procedure thoroughness while minimizing procedure time.

描述（由申请人提供）： 项目总结/摘要 拟议的快速通道工作旨在整合InterScience的C-View成像技术，能够为单个图像平面提供不受限制的240度垂直和360度全景视野，以及远端传感器技术，创新的照明方案和半刚性内窥镜包装。C-View半刚性内窥镜广泛适用于泌尿外科手术、腹腔镜手术和内窥镜普外科手术。具体而言，在泌尿外科，该技术不仅将增强整个膀胱和尿道的可视化，而且还将辅助大多数泌尿外科内窥镜手术，例如膀胱活检和电灼、用于逆行肾盂造影的输尿管口插管或导丝通过、膀胱内注射和经尿道切除术。使用这种创新技术，检查膀胱，拍摄膀胱病变和其他疾病过程将有助于未来的监测，更精确地定位先前的治疗。全视野、单视野通过消除各种成角内窥镜的术中交换和/或柔性内窥镜头端的操纵，最大限度地减少了手术时间和患者不适，同时确保了手术的彻底性。申报内窥镜的总体设计是内窥镜技术的巨大进步，利用了光学设计、光学组件制造、成像传感器和照明技术的最新技术。基于该技术的高度商业性质和对微创手术应用的影响，正在通过快速通道寻求这一应用。为了简化C-View半刚性内窥镜的研发过程，第一阶段的工作旨在为第二阶段的持续开发工作和后续商业化提供设计、测试和台架演示基础。拟议的第II阶段工作的总体目标是在第I阶段建立的基础上，通过工作原型和尸体模型测试的集成和组装来推进C-View内窥镜的开发。 项目叙述 C-View半刚性内窥镜特别适用于膀胱癌监测，但也将为泌尿外科手术、腹腔镜检查和内窥镜普通外科手术提供更广泛的受益。该C-View半刚性内窥镜前所未有的超宽视野将大大提高图像一致性和手术彻底性，同时最大限度地缩短手术时间。