A Weight Loss Program for Obese Black Women with OA

患有 OA 的肥胖黑人女性的减肥计划

• 批准号: 6492906
• 负责人: Carol J Henderson
• 金额: $ 9.42万
• 依托单位: GEORGIA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6492906
• 关键词: African American; adult human (21+); behavioral /social science research tag; dietary control; disease /disorder prevention /control; educational resource design /development; exercise; female; health behavior; human subject; human therapy evaluation; knee; nutrient intake activity; nutrition education; nutrition related tag; obesity; osteoarthritis; patient oriented research; psychobiology; quality of life; questionnaires; racial /ethnic difference; statistics /biometry; weight loss; women's health

DESCRIPTION (provided by applicant): African American (AA) women are at increased risk for obesity and the subsequent development of knee OA. A modest weight loss of 5-10% of baseline weight has been shown to reduce pain, functional disability, and improve gait in patients with knee OA. No culturally sensitive comprehensive weight loss programs combining diet and exercise have been developed for AA women with knee OA. We will test the hypothesis that overweight or obese, low socioeconomic (SES), urban AA women with knee OA who participate in a culturally sensitive dietary and physical activity behavior change pilot intervention for 3 months will experience at least a 5% reduction in their baseline body weight. It is also hypothesized that post-intervention 6-minute walking distance will improve compared to baseline. Specific Aim 1: To gain an understanding of behavioral and psychosocial determinants of dietary intake, eating patterns, and physical activity, a review of the literature and discussions with researchers, practitioners, and local community leaders will be performed. Specific Aim 2: Conduct exploratory focus groups to qualitatively evaluate factors that influence fruit/vegetable (F&V), fat intake, calorie-containing beverage consumption (CCB), and physical activity. Specific Aim 3: Develop new or modify existing dietary and physical activity-related educational materials and evaluation instruments for use in the pilot weight loss intervention. Specific Aim 4: Conduct focus groups to pre-test the cultural sensitivity and potential salience of intervention messages and materials. Specific Aim 5: Perform a 3-month pilot intervention to assess weight and maximal walking distance and the feasibility of implementing the culturally sensitive weight loss program. Methodology: A pre-post repeated measures design will be implemented in at least 36 overweight or obese AA women with knee OA. Primary outcomes are % weight change from baseline body weight and % change in 6minute maximum walking distance from baseline. Daily walking distance will be determined using pedometers. Other outcomes include dietary, physical activity, pain, functional ability, and stage of change assessment that will be performed at baseline and 3 months. Long-term goals: Conduct a prospective RCT in overweight or obese, low SES, urban AA women with knee OA utilizing the newly developed culturally sensitive weight loss program, and study the longevity of sustained weight loss.

描述（由申请人提供）： 非裔美国人（AA）妇女的肥胖风险增加 随后的膝盖OA发育。体重减轻的基线5-10％ 体重已显示可减轻疼痛，功能障碍并改善步态 在膝盖OA的患者中。没有文化敏感的全面减肥 饮食和运动结合的程序已针对膝盖的AA女性开发 OA。我们将检验以下假设，即超重或肥胖，低社会经济 （SES），城市AA妇女的膝盖OA，参加文化敏感的 饮食和身体活动行为改变了3个月的试验干预 其基线体重至少会降低5％。这是 还假设干预后6分钟的步行距离将有所改善 与基线相比。 特定目的1：了解行为和社会心理 饮食摄入量，饮食模式和体育锻炼的决定因素， 与研究人员，从业人员以及 将执行当地社区领导人。 特定目的2：进行探索性焦点小组进行定性评估 影响水果/蔬菜（F＆V），脂肪摄入，含卡路里的因素 饮料消费（CCB）和体育锻炼。 特定目标3：开发新的或修改现有的饮食和身体 与活动有关的教育材料和评估工具 飞行员减肥干预措施。 特定目的4：进行焦点小组以预测试文化敏感性和 干预信息和材料的潜在显着性。 具体目标5：执行3个月的试点干预以评估体重和 最大的步行距离和在文化上实施的可行性 敏感的减肥计划。 方法论：将在AT中实施预先重复的措施设计 至少有36个超重或肥胖的妇女膝盖OA。主要结果是％ 重量从基线体重变化，最大步行的％变化％变化 距基线的距离。每日步行距离将使用 计数器。其他结果包括饮食，体育锻炼，疼痛，功能 能力和变更评估阶段，将在基线和 3个月。 长期目标：在超重或肥胖，低SES中进行前瞻性RCT， Urban AA膝盖妇女使用新发展的文化敏感 减肥计划，并研究持续体重减轻的寿命。