CORE FACILITIES--DIFFRACTION AND COMPUTING

核心设施——衍射和计算

• 批准号: 6411529
• 负责人: FREDERIC M RICHARDS
• 金额: $ 17.42万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6411529
• 关键词: X ray crystallography; bioimaging /biomedical imaging; biomedical equipment; biomedical facility; computer data analysis

The CORE laboratory provides and maintains facilities for X-ray crystallographic investigation of macromolecular systems and for extensive computation related to data collection, reduction and analysis. Molecular Graphics systems play a special role in crystallographic problems and are extensively represented in the CORE laboratory. In addition to the service function, the CORE staff play a major role in the development of new instruments and procedures. Current examples are the remote controlled mirrors system for increasing the intensity of laboratory X-ray sources and the DENZO/SCALEPAK data reduction and scaling program package, all now widely used in the field of structural Biology.

CORE实验室提供并维护X射线设备 大分子系统的晶体学研究， 与数据收集、减少和分析有关的计算。分子 图形系统在晶体学问题中起着特殊的作用， 在CORE实验室中广泛使用。除了服务 核心工作人员在开发新的 工具和程序。 当前的例子是远程控制 提高实验室X射线源强度的反射镜系统 以及DENZO/SCALEPAK数据缩减和缩放程序包， 广泛应用于结构生物学领域。