CORE FACILITIES--DIFFRACTION AND COMPUTING

核心设施——衍射和计算

• 批准号: 6576895
• 负责人: FREDERIC M RICHARDS
• 金额: $ 17.42万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6576895
• 关键词: X ray crystallography; bioimaging /biomedical imaging; biomedical equipment; biomedical facility; computer data analysis; macromolecule

The CORE laboratory provides all members of the Yale Center for Structural Biology facilities for the investigation of macromolecular systems by X-ray crystallography and X-ray small-angle scattering, including instruments for data collection and computers for data reduction and analysis. Since molecular graphics is vital to these activities, the CORE laboratory includes several such systems and is constantly upgrading its capabilities in this and all other areas of concern. In addition to the services it supplies to the users of the CORE laboratory, which includes instrument and computer maintenance and help with both kinds of devices, the CORE staff develops new instruments and procedures. The CSB web site, which enables users to access the programs and data bases that are generally useful to structural biologists, with documentation, is a recent example of a CORE laboratory development useful to the structural biology community both inside and outside Yale.

CORE实验室为耶鲁结构生物学中心的所有成员提供了通过X射线晶体学和X射线小角散射研究大分子系统的设施，包括数据收集仪器和数据简化和分析计算机。由于分子图形对这些活动至关重要，CORE实验室包括几个这样的系统，并不断提高其在这一领域和所有其他领域的能力。除了向核心实验室的用户提供服务外，包括仪器和计算机维护以及这两种设备的帮助，核心工作人员还开发新的仪器和程序。CSB网站，使用户能够访问程序和数据库，通常是有用的结构生物学家，与文档，是一个核心实验室的发展有用的结构生物学社区内外耶鲁大学的一个最近的例子。