CORE FACILITIES--DIFFRACTION AND COMPUTING

核心设施——衍射和计算

• 批准号: 6271722
• 负责人: FREDERIC M RICHARDS
• 金额: $ 23.79万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6271722
• 关键词: X ray crystallography; biomedical facility; computer data analysis

The CORE laboratory provides and maintains facilities for X-ray crystallographic investigation of macromolecular systems and for extensive computation related to data collection, reduction and analysis. Molecular Graphics systems play a special role in crystallographic problems and are extensively represented in the CORE laboratory. In addition to the service function, the CORE staff play a major role in the development of new instruments and procedures. Current examples are the remote controlled mirrors system for increasing the intensity of laboratory X-ray sources and the DENZO/SCALEPAK data reduction and scaling program package, all now widely used in the field of structural Biology.

核心实验室提供和维护X光设备 大分子体系的结晶学研究及其广泛的应用 与数据收集、归并和分析相关的计算。分子 图形系统在结晶学问题中扮演着特殊的角色，并且 在核心实验室中有广泛的代表。除了这项服务之外 职能，核心员工在新世纪的发展中发挥着重要作用 仪器和程序。当前的例子是远程控制的 提高实验室X射线源强度的反射镜系统 以及Denzo/SCALEPAK数据缩减和缩放程序包，所有这些都是现在 广泛应用于结构生物学领域。