FAMILY BASED VERSUS ADOLESCENT RESIDENTIAL DRUG TREATMENT

基于家庭的药物治疗与青少年住宅药物治疗

• 批准号: 6477418
• 负责人: Howard Arthur Liddle
• 金额: $ 16.54万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2002-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6477418
• 关键词: adolescence (12-20); behavioral /social science research tag; clinical research; drug abuse therapy; family therapy; health care cost /financing; human subject; human therapy evaluation; residential care facility

During the past several years, statistics from national samples of high school youth indicate alarming increases in rates of substance use. The primary aims of the proposed study are to: 1) experimentally compare the effectiveness of family-based treatment, Multidimensional Family Therapy (MDFT), with adolescent residential treatment, Adolescent Treatment Program (ATP), in ameliorating drug use and symptoms of co-morbidity among dually diagnosed adolescents; 2) identify the mechanisms by which each treatment achieves its effects; and 3) examine the cost effectiveness and cost off-set of each treatment. ATP is a multifaceted residential treatment based on a social learning approach. MDFT is a multidimensional and intensive, in-home family-based treatment that targets individual, familial, peer, and community influences on drug use. An experimental design is achieved by randomly assigning 200 dually diagnosed adolescents to 2 treatments (MDFT, ATP). Comprehensive assessments of outcome (drug abuse, conduct problems/delinquency, and psychosocial functioning) and change mechanisms (parenting, alliance, 12 step, and adolescent skills) are obtained at 6 time points (intake; 2, 4, 12, 18 months post-intake and termination). Measures of cost effectiveness and cost off-set are included as well as careful procedures for treatment integrity and its measurement. Analyses will include Hierarchical Linear Modeling, Structural Equation Modeling, Multiple Regression, and MANOVA, and utilize latent factor scores representing multiple perspectives on multiple traits.

在过去几年中，国家抽样的统计数据显示， 在校青年使用药物的比率增加得令人震惊。的 该研究的主要目的是：1）实验比较 家庭治疗的有效性，多维家庭治疗 （MDFT），有青少年住院治疗，青少年治疗 在改善吸毒和共病症状方面， 双重诊断的青少年; 2）确定每个机制， 治疗达到其效果;以及3）检查成本效益， 每次治疗的费用抵消。ATP是一个多方面的住宅 基于社会学习方法的治疗。MDFT是一个多维 以及针对个人的、以家庭为基础的强化家庭治疗， 家庭，同伴和社区对药物使用的影响。 实验设计是通过随机分配200双 确诊的青少年接受2种治疗（MDFT、ATP）。全面 结果评估（药物滥用、行为问题/犯罪，以及 心理社会功能）和变化机制（养育，联盟，12 步骤和青少年技能）在6个时间点（摄入; 2，4， 入组和终止后12、18个月）。成本效益计量 和成本抵消包括以及仔细的程序， 完整性及其测量。分析将包括分层线性 建模、结构方程建模、多元回归和MANOVA， 并利用潜在因素得分代表多个观点， 多重特征