DNA probes containing solvatochromic fluorescent tags
DNA probes containing solvatochromic fluorescent tags
批准号:
1947182
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --
中文摘要
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英文摘要
I wish to be attached to the Tucker group, where I undertook my masters project. The group's research comprises of modified DNA and DNA sensing. The group have developed an anthracene DNA sensor for the detection of SNPs. Following on from this work, the project of interest to me consists of developing naphthalimide tagged DNA as a sensor to detect cancer cells. The sensor will be quantitative, detecting the percentage of changed bases, which is important for determining whether the cell is cancerous. Fluorescence will be monitored by UV absorption and TM studies, techniques which I am familiar with after performing them throughout my masters project. These sensors have exciting possibilities to be used clinically, removing cancerous tissue during operations. The cancerous tissue would fluoresce allowing easy excision from the surrounding healthy tissue.
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国内基金
海外基金
基于Van Allen Probes观测的地球辐射带电子反转能谱演化过程和物理机制研究
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批准号:--
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项目类别:--
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资助金额:55万元
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批准年份:2022
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负责人:顾旭东
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依托单位:
基于padlock probes对高度降解DNA检材进行法医学个体识别的研究
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批准号:30772460
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项目类别:面上项目
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资助金额:25.0万元
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批准年份:2007
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负责人:王保捷
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依托单位: