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Nitric Oxide, Endothelial Dysfunction and Diabetes

Nitric Oxide, Endothelial Dysfunction and Diabetes
一氧化氮、内皮功能障碍和糖尿病
批准号:
6445809
负责人:
SANGEETA R KASHYAP
金额:
$5.44万
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
未结题
起止时间:
2002-04-01 至

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中文摘要
翻译
此应用程序所基于的假设是 内皮型一氧化氮合酶受损是胰岛素的早期缺陷 2型糖尿病前的抵抗力与血管 疾病的并发症。有合适的患者群体 为了研究体内的生理参数,这些参数将被关联 并对活检的肌肉进行相关的生化测量。
英文摘要
The hypothesis on which this application is based is that impaired endothelial Nitric Oxide Synthase (NOS) is an early defect in insulin resistance that precedes type 2 diabetes and correlates with vascular complications of the disease. An appropriate patient population is available for studying the in vivo physiological parameters, which will be correlated with relevant biochemical measurements to be performed on biopsied muscle.
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Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes - (ARMMS-T2D)
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海外基金