Nitric Oxide, Endothelial Dysfunction and Diabetes
Nitric Oxide, Endothelial Dysfunction and Diabetes
批准号:
6445809
负责人:
SANGEETA R KASHYAP
金额:
$5.44万
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
未结题
起止时间:
2002-04-01 至
关键词:
biopsy blood glucose blood tests blood vessel disorder cardiovascular disorder epidemiology clinical research diabetes mellitus genetics disease /disorder proneness /risk gene expression hormone regulation /control mechanism human subject insulin sensitivity /resistance nitric oxide nitric oxide synthase noninsulin dependent diabetes mellitus polymerase chain reaction protein structure function vascular endothelium western blottings
中文摘要
本申请所基于的假设是,
内皮型一氧化氮合酶(NOS)受损是胰岛素抵抗的早期缺陷,
抵抗先于2型糖尿病并与血管
疾病的并发症。有适当的患者人群
用于研究体内生理参数,这些参数将与
并对活组织检查的肌肉进行相关的生物化学测量。
英文摘要
The hypothesis on which this application is based is that
impaired endothelial Nitric Oxide Synthase (NOS) is an early defect in insulin
resistance that precedes type 2 diabetes and correlates with vascular
complications of the disease. An appropriate patient population is available
for studying the in vivo physiological parameters, which will be correlated
with relevant biochemical measurements to be performed on biopsied muscle.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes - (ARMMS-T2D)
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批准号:10004639
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项目类别:
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资助金额:$186.07万
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财政年份:2017
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负责人:SANGEETA R KASHYAP
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依托单位:
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D Trial
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批准号:8730266
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项目类别:
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资助金额:$7.75万
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财政年份:2010
-
负责人:SANGEETA R KASHYAP
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依托单位:
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D Trial
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批准号:8277282
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项目类别:
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资助金额:$64.62万
-
财政年份:2010
-
负责人:SANGEETA R KASHYAP
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依托单位:
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D Trial
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批准号:8322275
-
项目类别:
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资助金额:$6.18万
-
财政年份:2010
-
负责人:SANGEETA R KASHYAP
-
依托单位:
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D Trial
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批准号:7992982
-
项目类别:
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资助金额:$56.51万
-
财政年份:2010
-
负责人:SANGEETA R KASHYAP
-
依托单位:
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D Trial
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批准号:8110551
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项目类别:
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资助金额:$55.82万
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财政年份:2010
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负责人:SANGEETA R KASHYAP
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依托单位:
GLUCOSE METABOLISM IN THE IMMEDIATE AND SHORT-TERM FOLLOW-UP AFTER BARIATRIC
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批准号:7608209
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项目类别:
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资助金额:$0.08万
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财政年份:2007
-
负责人:SANGEETA R KASHYAP
-
依托单位:
PLASMA FREE FATTY ACIDS, ENDOTHELIAL DYSFUNCTION, AND THE ROLE OF NOS PATHWAY
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批准号:7608194
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项目类别:
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资助金额:$0.72万
-
财政年份:2007
-
负责人:SANGEETA R KASHYAP
-
依托单位:
PLASMA FREE FATTY ACIDS, ENDOTHELIAL DYSFUNCTION, AND THE ROLE OF NOS PATHWAY
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批准号:7377720
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项目类别:
-
资助金额:$5.15万
-
财政年份:2006
-
负责人:SANGEETA R KASHYAP
-
依托单位:
Nitric Oxide, Endothelial Dysfunction and Diabetes
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批准号:6622398
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项目类别:
-
资助金额:$1.55万
-
财政年份:2002
-
负责人:SANGEETA R KASHYAP
-
依托单位:
海外基金