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Exploring the impact of the early obesogenic home environment on children's growth and psychological development.

探讨早期致胖的家庭环境对儿童成长和心理发展的影响。

基本信息

批准号：
1948633
负责人：
金额：
--
依托单位：
University of Leeds
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2017
资助国家：
英国
起止时间：
2017 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=studentship-1948633
关键词：
Exploring impact early obesogenic home

项目摘要

Background In 2015, 21.9% of children aged 4-5 and 33.3% of those aged 10-11 were either overweight (OW) or obese (OB) (PHE, 2017). OW and OB are associated with complex co-morbidities such as type 2 diabetes mellitus and psychosocial disturbances (Lakshman et al., 2012). The early home environment (HE) plays a critical role in the development of food preferences, eating behaviours and health in later life (Birch & Anzman, 2010). Objectives To examine: The effect of aspects of the early obesogenic HE on children's psychological and physiological development during childhood and how this tracks into adolescence. Geneenvironment interactions to assess the impact of early obesogenic HE on weight development based on genetic risk. Aspects of the HE within low socio-economic groups and to compare how early obesogenic HEs vary between different socio-economic groups. Hypothesis Aspects of the early obesogenic HE influence the physiological and psychological development of young people. Significance Recent NCMP figures highlight that more and more children are becoming OB before entering primary school. Previous research highlights that experiences during early childhood play a key role in increasing the risk of OB (Birch & Anzman, 2010). Little research has been conducted to longitudinally evaluate the role early environmental, biological and psychosocial experiences have on psychological and physiological development by early adolescence. This research will use advanced quantitative methods to provide a clear framework for examining how various early life environmental, biological and behaviouralfactors affect psychological and physiological development during childhood and adolescence. This research will be used to ascertain early life predictors of growth and weight development and psychological outcomes (e.g. self-esteem, body image, disordered eating behaviours). The findings will be used to: inform the design of future interventions, make public health recommendations for modifying the HE to reduce risk of adverse physiological and psychological outcomes. Method Systematic review and meta-analysis of published data on the relationship between aspects of the early obesogenic HE and child body weight trajectory. Secondary data analysis of data from the Gemini Twin birth cohort study, a large sample of 2402 families with twins born in the UK in 2007. The dataset will be used to: Explore the influence of aspects of the early HE such as meal times, food accessibility/ availability, social, media and parental modelling on growth development and weight in young adolescence. Explore, using general linear models how these aspects of early HE influence psychosocial development (e.g. self-esteem) and the development of eating behaviours (e.g. food preferences) in young people. Use the twin method to explore the relative contributions of genes and HEs to growth and eating behaviour in childhood and examine gene-environment interactions to ascertain if the influence of the early HE mediates genetic risk of obesity in later childhood. Assess the extent to which the early HE accurately predicts child growth and weight development by using weight trajectory models. In the second phase of the research, data will be collected from low SES families using the HE questionnaire (HEQ), piloted in a low SES group to assess the usability of the measure in this sample. The measure will be adapted as required. The HEQ will then be used to collect new data in low SES families with children aged 4 years to mirror the Gemini study. These findings will be used to examine the obesogenic nature of the early HE in low SES families and compare these findings with the higher SES families from the Gemini study. References Birch & Anzman (2010). Child Development Perspectives, 4(2), 138-143 Lakshman et al., (2012). Circulation, 126(14), 1770-1779 Public Health England (2017). http://www.noo.org.uk/NOO_about_obesity/child_obesity

2015年，21.9%的4-5岁儿童和33.3%的10-11岁儿童超重（OW）或肥胖（OB）（PHE，2017）。OW和OB与复杂的共病如2型糖尿病和心理社会障碍有关（Lakshman等人，2012年）。早期的家庭环境（HE）在食物偏好的发展中起着至关重要的作用，饮食行为和晚年的健康（Birch & Anzman，2010）。目的审查：早期致肥胖性HE对儿童心理和生理发育的影响，以及如何进入青春期。基于遗传风险评估早期致肥HE对体重发展的影响的基因环境相互作用。低社会经济群体中的HE方面，并比较不同社会经济群体之间早期致肥HE的差异。早期肥胖性HE影响青少年的生理和心理发展。最近的NCMP数字强调，越来越多的儿童在进入小学之前成为OB。以前的研究强调，儿童早期的经历在增加OB风险方面起着关键作用（Birch & Anzman，2010）。很少有研究进行了纵向评估的作用，早期的环境，生物和心理社会的经验，心理和生理发展的早期青春期。这项研究将采用先进的定量方法，为研究各种早期生活环境，生物和行为因素如何影响儿童和青少年时期的心理和生理发展提供一个明确的框架。这项研究将用于确定早期生活中的生长和体重发展以及心理结果（例如自尊，身体形象，饮食行为紊乱）的预测因素。研究结果将用于：为未来干预措施的设计提供信息，为修改HE以降低不良生理和心理后果的风险提出公共卫生建议。方法系统回顾和荟萃分析已发表的数据之间的关系方面的早期肥胖性HE和儿童体重轨迹。双子座双胞胎出生队列研究数据的二次数据分析，2007年在英国出生的2402个双胞胎家庭的大样本。该数据集将用于：探索早期HE的各个方面的影响，如用餐时间，食物可获得性/可用性，社交，媒体和父母对青少年生长发育和体重的建模。探索，使用一般的线性模型如何早期HE这些方面影响心理社会发展（如自尊）和饮食行为（如食物偏好）在年轻人的发展。使用双胞胎方法探索基因和HE对儿童期生长和饮食行为的相对贡献，并检查基因-环境相互作用，以确定早期HE的影响是否介导儿童后期肥胖的遗传风险。通过使用体重轨迹模型评估早期HE准确预测儿童生长和体重发育的程度。在研究的第二阶段，将使用HE问卷（HEQ）从低SES家庭收集数据，在低SES组中进行试点，以评估该措施在该样本中的可用性。这项措施将根据需要加以调整。然后，HEQ将用于收集有4岁儿童的低SES家庭的新数据，以反映Gemini研究。这些研究结果将用于检查低SES家庭中早期HE的致肥胖性质，并将这些结果与Gemini研究中SES较高的家庭进行比较。Birch & Anzman（2010）. Child Development Perspectives，4（2），138-143 Lakshman et al.，（2012年）。Circulation，126（14），1770-1779 Public Health England（2017）. http://www.noo.org.uk/NOO_about_obesity/child_obesity