BIOMEDICAL RESEARCH EXPERIENCES FOR NON-BIOLOGY MAJORS

这项申请是为了响应RFA为来自不同的非生物学背景的本科生提供生物医学科学暑期研究经验。随着解决生物学问题的跨学科方法的需求日益增加，我们必须改变未来研究人员的培训方式。特别是，这将是一笔巨大的财富，可以吸引拥有更强量化技能的学生。虽然跨学科领域的研究生课程通常是可用的，比如坎比在纽约州立大学布法罗分校开设的研究生课程，但对许多学生来说，在他们的职业轨迹已经确定的时候，这已经太晚了。目前的计划寻求在本科阶段进行干预，让目前处于更多物理科学轨道的学生接触到生物医学科学提供的丰富机会。拟议了一个为期10周的综合暑期计划，每年向10名学生提供若干领域之一的研究经验，并结合生物医学科学当前主题的一系列短期课程、面向职业机会的一系列研讨会以及对当地研究机构的实地考察。该计划导师所代表的研究领域包括：组织生物工程；致病机制；神经疾病和发育的分子分析；细胞内和细胞内信号机制的细胞生物学；离子通道的生物物理学；以及大分子结构分析。参加该项目的学生将在第一周对实验室技术以及该项目提供的研究机会进行初步了解。在项目结束时，学生们将在坎比所有实验室的会议上展示他们的工作，这是秋季课程开始前预定的研究务虚会的一部分。将通过专门的网页进行广泛的努力，以宣传学生研究的结果，并作为一种手段来跟踪离开该计划的学生，以评估其有效性。

This application is in response to an RFA for providing Summer Research Experiences in Biomedical Science for undergraduates who come from distinct, non-biological backgrounds. With the increasing need for interdisciplinary approaches to solving biological problems, it is imperative that we modify the way in which the researchers of tomorrow are trained. Particularly, it would be a great asset to attract students with greater quantitative skills. While graduate programs in interdisciplinary areas, such as that run at SUNY at Buffalo by CAMBI, are often available, for many students this occurs too late at a time in which their career track has been set. The current program seeks to intervene during the undergraduate years to expose students, who are currently in more physical science tracks, to the wealth of opportunities provided in the biomedical sciences. An integrated 10 week summer program is proposed that would provide 10 students each year with a research experience in one of several areas, combined with a series of short courses in current topics in the biomedical sciences, a seminar series geared towards career opportunities, and field trips to local research facilities. Research areas represented among the mentors of the program include: tissue bioengineering; mechanisms of pathogenic; molecular analysis of neurological disorders and development; cell biology of inter- and intra- cellular signaling mechanisms; biophysics of ion channels, and; structural analysis of macromolecules. Students in the program would be given an initial orientation to lab techniques, and to the research opportunities available within the program in their first week. At the close of the program, the students will present their work at a meeting of all of the CAMBI labs as part of a research retreat scheduled prior to the beginning of Fall classes. Extensive efforts through a dedicated web page will be used to publicize the results of the student research, and as a means of tracking students who leave the program to assess its effectiveness.